Results 71 to 80 of about 1,342,717 (316)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Penyebab Penyakit Layu pada Tanaman Semangka di Karawang, Jawa Barat

Jurnal Fitopatologi Indonesia, 2013
Wilt disease of watermelon is an important disease in Indonesia, but determination of the causal agent has not been reported yet. Postulat Koch based approach was conducted to determine the pathogen causing wilt of watermelon from Karawang, West Java ...
Kartini Budiastuti, Efi Toding Tondok, Suryo Wiyono   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Benefits from ecological study methods to taxonomy of enchytraeids in southern Mata Atlântica Benefícios de métodos de estudos ecológicos para a taxonomia de enquitreídeos no sul da Mata Atlântica

Pesquisa Agropecuária Brasileira, 2009
The objective of this work was to determine how taxonomy benefited from the ecological quantitative and site-based sampling methods in enchytraeids studies.
Rüdiger Maria Schmelz, Rut Maria Collado de la Peña, Jörg Römbke   +2 more
doaj   +1 more source

Mitochondrial cox1 sequence data reliably uncover patterns of insect diversity but suffer from high lineage-idiosyncratic error rates. [PDF]

, 2010
The demand for scientific biodiversity data is increasing, but taxonomic expertise is often limited or not available. DNA sequencing is a potential remedy to overcome this taxonomic impediment.
Ribera Ignacio, Hendrich, Lars, Pons, Joan, Balke, Michael, Ribera, Ignacio, Michael Balke, Balke Michael, Hendrich Lars, Lars Hendrich, Joan Pons, Pons Joan, Ignacio Ribera   +11 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Caracterização e descrição da estrutura anatômica do lenho de seis espécies arbóreas com potencial medicinal Characterization and description of wood anatomical structure in six tree species with medicinal potential

Revista Brasileira de Plantas Medicinais, 2011
A caracterização morfoanatômica e a correta identificação das plantas medicinais são fundamentais para o controle de qualidade dos fitoterápicos. No presente trabalho é caracterizada a anatomia do lenho visando à identificação de seis espécies arbóreas ...
G. Cury, M. Tomazello-Filho
doaj   +1 more source

DNA-barcoding and Species Identification for Some Saudi Arabia Seaweeds using rbcL Gene

, 2019
Among the different biological sources, seaweeds have lot of biotechnological applications. Saudi Arabia is bounded by three bodies of water. With a coastal border of almost 1,800 km.
Omar Bahattab, Mohammed Ali Alshehri, Othman Alzahrani, Gamal Osman, Shafik Ibrahim, Abdulrahman Alasmari, Al Thabiani Aziz   +6 more
core   +1 more source