BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Species richness and species composition of fungal communities associated with cellulose decomposition at different altitudes on the Tibetan Plateau [PDF]
, 2009 Dai Hirose +7 more
openalex +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
DiversityFish play an important role in river ecosystems, and the conservation of their diversity is a common goal worldwide. It is still unclear how fish monitoring programs should be developed in order to rationalize the monitoring of fish diversity in rivers ...
Mingqiao Yu +3 more
doaj +1 more source
Year-Round Bat Activity and Species Richness Near Temporary Ponds in the Mediterranean Region [PDF]
, 2023 Ioanna Salvarina +5 more
openalex +1 more source
Forest ecosystem research in Hainich National Park (Thuringia) : first results on flora and vegetation in stands with contrasting tree species diversity [PDF]
, 2006 A floristic description is presented of the study sites of the Research Training Group “The role of biodi-versity for biogeochemical cycles and biotic interactions in temperate deciduous forests”.
Bernhardt-Römermann, Markus +2 more
core
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Global Ecology and ConservationTraditional island biogeography posits that area and remoteness are key determinants of species richness. However, this theory is challenged by recent changes in species dispersal patterns caused by human activity and climate change.
Saiqiang Li +4 more
doaj +1 more source
Psyche: A Journal of Entomology, 2011 A continuing challenge in orthopteran ecology is to understand what determines grasshopper species diversity at a given site. In this study, the objective was to determine if variation in grasshopper abundance and diversity between 23 sites in western ...
David H. Branson
doaj +1 more source