Results 101 to 110 of about 13,050,965 (387)

Abrogation of species specificity for activation of tumoricidal properties in macrophages by recombinant mouse or human interferon-gamma encapsulated in liposomes.

open access: yesJournal of Immunology, 1985
Highly purified human blood monocytes, isolated by continuous Percoll density gradients under endotoxin-free conditions, and mouse peritoneal exudate macrophages (PEM) were activated in vitro by the combination of muramyl dipeptide (MDP) and recombinant ...
Isaiah J. Fidler   +3 more
semanticscholar   +1 more source

Species-specific temperature sensitivity of TRPA1 [PDF]

open access: yesTemperature, 2015
Transient receptor potential ankyrin 1 (TRPA1) is a polymodal ion channel sensitive to temperature and chemical stimuli. The importance of temperature and aversive chemical detection for survival has driven the evolutionary diversity of TRPA1 sensitivity.
Willem J. Laursen   +4 more
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion

open access: yesFrontiers in Pharmacology, 2014
One approach to experimental science involves creating hypotheses, then testing them by varying one or more independent variables and assessing the effects of this variation on the processes of interest.
Douglas Bruce Kell   +1 more
doaj   +1 more source

Chemical Competition between Microscopic Stages of Macrocystis pyrifera and Five Native Kelp Species: Does Giant Kelp Always Lose? [PDF]

open access: yes, 2018
The giant kelp Macrocystis pyrifera is often considered competitively dominant to other kelp species due to its high productivity. However, on the microscopic level, previous studies found that Macrocystis can be inferior to other kelp species through ...
Christensen, Maria Suzanne
core   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Substrate specificity of glucokinase and fructokinase of several conifer species

open access: yesActa Societatis Botanicorum Poloniae, 2014
Annual plant species were found to have several distinct classes of hexokinases which are specific for different hexoses, such as glucose, fructose and mannose.
Fritz Bergmanni, Leon Mejnartowicz
doaj   +1 more source

specificity: an R package for analysis of feature specificity to environmental and higher dimensional variables, applied to microbiome species data

open access: yesEnvironmental Microbiome, 2022
Background Understanding the factors that influence microbes’ environmental distributions is important for determining drivers of microbial community composition.
John L. Darcy   +4 more
doaj   +1 more source

Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rDNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and Ireland hospitals [PDF]

open access: yes, 2014
Infective endocarditis (IE) can be diagnosed in the clinical microbiology laboratory by culturing explanted heart valve material. We present a service evaluation that examines the sensitivity and specificity of a broad-range 16S rDNA polymerase chain ...
Alshafi, K   +8 more
core   +1 more source

Software for the Analysis of Species-Specific Vocalizations [PDF]

open access: yesActa Medica (Hradec Kralove, Czech Republic), 2004
Vocalization calls are behaviorally relevant complex sounds that typically contain several harmonics and show frequency and amplitude modulation. In this paper, an introduction to a software tool for the analysis of species-specific vocalizations is presented.
Martin Komárek   +3 more
openaire   +4 more sources

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