Results 211 to 220 of about 1,256,681 (354)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Non-<i>Helicobacter pylori Helicobacters</i>, a Treatable Provocateur of Parkinson's Disease: Hypothesis, Evidence and Species Specificity. [PDF]

Int J Mol Sci
Wang W, Smith M, Ellis R, Savio A, Nevel A, Umamahesan C, Pavlidis P, Hayee BH, Taylor D, Young AH, Charlett A, Dobbs SM, Dobbs RJ.   +12 more
europepmc   +1 more source

Characterizing the original anti-C5 function-blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5. [PDF]

Immunology, 2020
Zelek WM, Menzies GE, Brancale A, Stockinger B, Morgan BP.   +4 more
europepmc   +1 more source

Additional file 5: of Computational approach to predict species-specific type III secretion system (T3SS) effectors using single and multiple genomes

, 2016
Christopher Hobbs, Vanessa Porter, Maxwell Stow, Bupe A. Siame, Herbert H. Tsang, Ka Nang Leung   +5 more
openalex   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Vitamin D-regulated Gene Expression Profiles: Species-specificity and Cell-specific Effects on Metabolism and Immunity.

Endocrinology, 2021
Dimitrov V, Barbier C, Ismailova A, Wang Y, Dmowski K, Salehi-Tabar R, Memari B, Groulx-Boivin E, White JH.   +8 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Species-Specific Immunodetection of an Entamoeba histolytica Cyst Wall Protein

, 2016
Lauren J. Spadafora, Moira R. Kearney, Abdullah Siddique, Ibne Karim M. Ali, Carol A. Gilchrist, Tuhinur Arju, Benjamin G. Hoffstrom, Felicia K. Nguyen, William A. Petri, Rashidul Haque, Gerard A. Cangelosi   +10 more
openalex   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Biomimetic Analogues of the Desferrioxamine E Siderophore for PET Imaging of Invasive Aspergillosis: Targeting Properties and Species Specificity. [PDF]

J Med Chem
Mular A, Hubmann I, Petrik M, Bendova K, Neuzilova B, Aguiar M, Caballero P, Shanzer A, Kozłowski H, Haas H, Decristoforo C, Gumienna-Kontecka E.   +11 more
europepmc   +1 more source