Results 61 to 70 of about 13,028,141 (393)

Evolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode Classification

open access: yesLife, 2015
Aminoacyl-tRNA synthetases (aaRSs) are enzymes that catalyze the transfer of amino acids to their cognate tRNAs as building blocks for translation. Each of the aaRS families plays a pivotal role in protein biosynthesis and is indispensable for cell ...
Pengfei Fang, Min Guo
doaj   +1 more source

Phase Transition in Two Species Zero-Range Process [PDF]

open access: yesJ. Phys. A: Math. Gen. 36 (2003) L441-L447, 2003
We study a zero-range process with two species of interacting particles. We show that the steady state assumes a simple factorised form, provided the dynamics satisfy certain conditions, which we derive. The steady state exhibits a new mechanism of condensation transition wherein one species induces the condensation of the other.
arxiv   +1 more source

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding*

open access: yesJournal of Biological Chemistry, 2011
Hypomorphic ADAM17ex/ex mice showed defects in mucosal regeneration due to inefficient enhanced GFR shedding. ADAM17 is the main sheddase of interleukin-6 receptor (IL-6R) to induce IL-6 trans-signaling. However, serum levels of soluble murine IL-6R were
Christoph Garbers   +8 more
semanticscholar   +1 more source

Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]

open access: yes, 2005
Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Andress   +15 more
core   +1 more source

Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity

open access: yesVirulence, 2021
Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus, causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%.
Satoko Yamaoka, Hideki Ebihara
doaj   +1 more source

Environ centrality reveals the tendency of indirect effects to homogenize the functional importance of species in ecosystems [PDF]

open access: yesFann, SL and SR Borrett. 2012. Environ centrality reveals the tendency of indirect effects to homogenize the functional importance of species in ecosystems. Journal of Theoretical Biology 294(7), 74-86, 2011
Ecologists and conservation biologists need to identify the relative importance of species to make sound management decisions and effectively allocate scarce resources. We introduce a new method, termed environ centrality, to determine the relative importance of a species in an ecosystem network with respect to ecosystem energy--matter exchange.
arxiv   +1 more source

Effects of chronic browsing on life‐history traits of an irruptive large herbivore population

open access: yesPopulation Ecology, EarlyView.
This study aimed to determine the relationship between diet quality, body mass, and size (hind foot length), and female reproduction and sought to identify the mechanism by which high density under severe food limitations is maintained. Our results demonstrated that sika deer introduced to Nakanoshima Island have maintained high densities through high ...
Koichi Kaji   +9 more
wiley   +1 more source

Absence of Behavioral Induction in Oviposition Preference of \u3ci\u3ePapilio Glaucus\u3c/i\u3e (Lepidoptera: Papilionidae) [PDF]

open access: yes, 2017
This study addressed the possible behaviora induction effects of previous exposure to several specific host plants on subsequent host preference hierarchy and specificity (i.e ..
Scriber, J Mark
core   +2 more sources

Cultivation of Wild Species from Goniolimon genera: a Case Study

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2008
During the period 1996-2001 three wild perennial Bulgarian plants belong to Plumbaginaceae family (Goniolimon tataricum Boiss., Goniolimon besserianum (Shut ex Reichenb.) and Goniolimon collinum (Griseb.)) were studied at the Floriculture Institute ...
A. KANINSKI, S. BISTRICHANOV
doaj   +1 more source

Zonadhesin Is Essential for Species Specificity of Sperm Adhesion to the Egg Zona Pellucida*

open access: yesJournal of Biological Chemistry, 2010
Interaction of rapidly evolving molecules imparts species specificity to sperm-egg recognition in marine invertebrates, but it is unclear whether comparable interactions occur during fertilization in any vertebrate species.
S. Tardif   +8 more
semanticscholar   +1 more source

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