Results 261 to 270 of about 56,098 (354)

Investigating the Causes of an Extinction Catastrophe: Controlling Introduced Predators Remains Essential for Conserving Australia's Mammals. [PDF]

Bioscience
Woinarski JCZ, Legge SM, Moseby K, Burbidge AA, Carthey AJR, Dickman CR, Doherty TS, Ferris J, Fisher DO, Hollanders M, Hradsky BA, Johnson CN, Jolly CJ, Kanowski J, Letnic M, Mason RT, McGregor H, Murphy BP, Pedler R, Read JL, Rendall AR, Stobo-Wilson A, Webb J, Webber BL, West R, Ritchie EG.   +25 more
europepmc   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

Canonical and noncanonical forms of G4 DNA at cluster III of the BCL6 breakpoint region could lead to chromosomal translocation in DLBCL. [PDF]

J Biol Chem
Javadekar SM, Das S, Hanumegowda SM, Kumari S, Choudhary B, Raghavan SC.   +5 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Application of Exon Primed Intron Crossing Markers to Cross-Amplify <i>Oreochromis</i> Species in Eastern Africa. [PDF]

Ecol Evol
Agoe C, Kwikiriza G, Akoll P, Tibihika PD, Curto M, Walakira J, Vijayan T, Nyauchi E, Kariuki J, Dornstauder-Schrammel E, Basooma R, Sonnenberg S, Meulenbroek P, Meimberg H.   +13 more
europepmc   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

Advanced Science, EarlyView.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao, Bingyao Bai, Xingqian Ye, Yiliang Lin   +3 more
wiley   +1 more source

Polyploid plant genomes complexity and the challenges of sequencing. [PDF]

Planta
Anderson AW, Albertini E, Rosellini D.
europepmc   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source