Results 281 to 290 of about 56,098 (354)

Translocation of polystyrene nanoplastics in distinct plant species: Novel insight from a split-root system and transcriptomic analysis

Xiang Xu, Cheng Peng, Jiaqi Tan, Qian Sui, Jing Wei, Chensi Shen, Wenwen Xie, Wei Zhang, Yongming Luo   +8 more
openalex   +2 more sources

CRISPR/Cas9‐Based Vanadium MXene‐Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal‐Induced Multi‐Effect Synergistic Antitumor Therapy

Advanced Science, EarlyView.
In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang, Feng‐Ming Li, Yi‐Fan Tu, Ke‐Ke Feng, Cheng‐Lei Li, Shi‐Cheng Tian, Yong‐Shan Hu, Jing‐Wei Shao, Zhen‐Hua Liu   +8 more
wiley   +1 more source

Translocated populations are genetically similar to natural populations and populations resulting from natural colonizations. [PDF]

PLoS One
Meléndez-Cal-Y-Mayor JF, Winkler J, Müller R, Lüscher B, Bolliger J, Ozgul A, Schmidt BR.   +6 more
europepmc   +1 more source

Additional file 3 of Reference genome bias in light of species-specific chromosomal reorganization and translocations

Marius F. Maurstad, Siv Nam Khang Hoff, Jose Cerca, Ravinet, Mark, Ian Bradbury, Kjetill S. Jakobsen, Kim Præbel, Jentoft Sissel   +7 more
openalex   +1 more source

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source

Comparative cytogenetics among populations of two <i>Bothriurus</i> species (Scorpiones, Bothriuridae). [PDF]

Comp Cytogenet
de Lima JF, Schneider MC, Carvalho LS, Pinto-da-Rocha R.   +3 more
europepmc   +1 more source

Reinforcing Calcium Overload via Inflammation‐Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

Advanced Science, EarlyView.
A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu, Yang Liu, Qin Fan, Jinqiao Zhang, Kexin Wen, Boyu Yuan, Xianzhou Cai, Ziliang Dong, Lianhui Wang   +8 more
wiley   +1 more source

Perspectives on the utilization of <i>Aegilops</i> species containing the U genome in wheat breeding: a review. [PDF]

Front Plant Sci
Badaeva ED, González Franco MJ, Razumova O, Tereshchenko NA, Divashuk M.   +4 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Genetic diversity and conservation implications for European Griffon Vultures (Gyps fulvus): Insights from mitochondrial D-loop HVR1. [PDF]

Sci Rep
Mereu P, Davidović S, Pirastru M, Arrondo E, Margalida A, Scarpa F, Blanco G, Oliva-Vidal P, Martínez JM, Tanasković M, Hribšek I, Günther T, Miranda PM, Donázar JA, Cortés-Avizanda A, Zapata JAS, Dobrev D, Arkumarev V, Stamenov A, Xirouchakis S, Choresh Y, Hatzofe O, Hadjisterkotis E, Sušić G, Muzzeddu M, Bogliolo L, Naitana S, Leoni GG.   +27 more
europepmc   +1 more source