Results 171 to 180 of about 9,610,877 (306)

RelabotulinumtoxinA, a Ready-to-Use Formulation Neuromodulator Manufactured with PEARL™ Technology to Maintain High Biological and Specific Activity. [PDF]

Toxins (Basel)
Ståhl U, Lekholm E, Hamnevik E, Fredriksson R, Shridharani SM, Taghetchian K, Cohen JL, Nestor MS, Liljegren Sundberg Å.   +8 more
europepmc   +1 more source

Motor cortical influence relies on task-specific activity covariation. [PDF]

Cell Rep, 2022
Warriner CL, Fageiry S, Saxena S, Costa RM, Miri A.   +4 more
europepmc   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Integrated In Vitro and In Silico Profiling of Piperazinyl Thiosemicarbazone Derivatives Against Trypanosoma cruzi: Stage-Specific Activity and Enzyme Inhibition. [PDF]

Pharmaceuticals (Basel)
Baldoni HA, Sbaraglini ML, Balcazar DE, Arias DG, Guerrero SA, Alba Soto CD, Cieslik W, Rogalska M, Polański J, Enriz RD, Jampilek J, Musiol R.   +11 more
europepmc   +1 more source

Studies of the Specific Activity of Aerosolized Isoniazid against Tuberculosis in a Mouse Model. [PDF]

Antibiotics (Basel), 2022
Valiulin SV, Onischuk AA, Baklanov AM, Dubtsov SN, Dultseva GG, An'kov SV, Tolstikova TG, Belogorodtsev SN, Schwartz YS.   +8 more
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Antibacterial effectors in Dictyostelium discoideum: specific activity against different bacterial species. [PDF]

mSphere
Munoz-Ruiz R, Lamrabet O, Jauslin T, Guilhen C, Bourbon A, Cosson P.   +5 more
europepmc   +2 more sources

A buffer-tuning strategy to profile domain-specific activity of chimeric I-TevI/CRISPR gene editors in vitro. [PDF]

Sci Rep
Loedige KW, White AL, McMurrough TA, Stead BE, Edgell DR.   +4 more
europepmc   +1 more source

Novel specific activity-based probes validate KLK proteases as druggable targets. [PDF]

Cancer Biol Ther, 2022
Sotiropoulou G, Zingkou E, Pampalakis G.
europepmc   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source