Results 121 to 130 of about 3,193,780 (374)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Estimation of General and Specific Combining Ability Effects for Quality Protein Maize Inbred Lines

, 2022
Goshime Muluneh Mekasha, Adefris Teklewold Chere, Hussein M. Ali, Dagne Wegary Gissa, Solomon Amassu Seyoum   +4 more
openalex   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Combining ability for yield and yield-associated traits in wheat (Triticum aestivum L.)

Electronic Journal of Plant Breeding
The current breeding effort aims to develop new wheat genotypes with higher genetic potential, thereby contributing to food security. Ten wheat genotypes were crossed in a half-diallel mating design.
Afsar Ahmad1 and Rajesh Kumar Gupta2
doaj   +1 more source

Heterosis and combining ability for yield and other agronomic traits in Triticale

Open Agriculture, 2018
The estimation of genetic parameters such as heterosis (Mh), heterobeltiosis (Hh), general combining ability (GCA) and specific combining ability (SCA) allows inferences about the predominant action of the genes, indicates the appropriate selection ...
Ferrari Enzo, Picca Aurora, Domínguez Rodolfo, Paccapelo Héctor   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The analysis of specific combining ability and heterosis in tomato [PDF]

, 2011
Cilj ovog istraživanja je bio da se za sedam komponenti prinosa (dužina i širina ploda, debljina perikarpa ploda, broj komora ploda, broj plodova po biljci, masa ploda i masa plodova po biljci) izvrši analiza posebnih kombinacionih sposobnosti i heterozisa u odnosu na boljeg roditelja na bazi srednjih vrednosti roditelja i njihovih dijalelnioh hibrida.
Živanović, Tomislav, Prodanović, Slaven, Šurlan-Momirović, Gordana, Đorđević, Radiša, Zdravković, Jasmina, Zečević, Bogoljub   +5 more
openaire   +1 more source

GENETIC STUDY OF BARLEY GERMINATION BEHAVIOUR II. GENERAL AND SPECIFIC COMBINING ABILITY [PDF]

Journal of the Institute of Brewing, 1960
Ten barley varieties were grouped according to the rate and evenness of germination or “germination behaviour” of their seed. Varieties R1 and S2 constituted the rapid; M3, M4, M5, M6, M6, M7 and M8 the medium; and S9and S10 the slow groups. A diallele crossing test was performed, in which the ten varieties were crossed with each other to produce all ...
openaire   +1 more source