Results 91 to 100 of about 13,372,123 (291)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Dynamic Analysis of the Cutting Head of a Transverse-Axis Roadheader

Applied Sciences
This study develops a theoretical framework for evaluating the dynamic response and energy performance of the EBH260 transverse-axis roadheader cutting head under horizontal swing cutting conditions.
Xuguang Liu, Shuogui Wang, Yunhao Kang
doaj   +1 more source

An analytical model for predicting specific cutting energy in whirling milling process

, 2019
The specific cutting energy (SCE) of machining processes is a significant indicator for machining sustainability. However, the characteristics of SCE in whirling milling as a promising green process are unknown because of the special material removal ...
Yan He, Le-Xiang Wang, Yu-Lin Wang, Yu-Feng Li, Shi-Long Wang, Yan Wang, Chao-Xun Liu, Chuanpeng Hao   +7 more
semanticscholar   +1 more source

Modeling and analysis of specific cutting energy of whirling milling process based on cutting parameters

Procedia CIRP, 2019
Specific cutting energy (SCE) is significant to manufacturing sustainability and directly relevant to energy efficient machining and quality of surface generation of machining processes.
Le-Xiang Wang, Yan He, Yu-Feng Li, Yu-Lin Wang, Chao-Xun Liu, Xuehui Liu, Yan Wang   +6 more
semanticscholar   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Impact of Blade Geometric Parameters on the Specific Cutting Energy of Willow (Salix viminalis) Stems

Applied Sciences
This article presents a model to estimate the specific energy demand for cutting annual willow stems, considering variations in plant moisture content and sliding-cutting angles. The study involved laboratory tests and statistical analyses.
Tomasz Nowakowski, Karol Tucki
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Analysis of selected functional parameters of saw chains

Journal of Forest Science
Results obtained from the research study focused on the functional parameters of five saw chains tested on a test bench equipped with an electrically driven chain saw brought a number of findings.
Pavel Nevrkla, Luboš Staněk, Jindřich Neruda   +2 more
doaj   +1 more source