Results 71 to 80 of about 8,961,128 (255)

Moisture dependent thermal properties of selected vegetables in Akwa Ibom State, Nigeria

Research in Agricultural Engineering, 2019
The thermal properties of some selected vegetables in Akwa Ibom State, Nigeria were investigated. The specific heat, thermal conductivity and thermal diffusivity for the five selected vegetables (Afang, Nkong, Atama, Editan and Nton) were determined and ...
Olugbenga Abiola Fakayode, Olayemi Olubunmi Ojoawo   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Evaluating the thermal insulation properties of sustainable building materials in Southern Algeria: A study on plaster and palm fibres

Budownictwo i Architektura
This research addresses the critical need to develop environmentally friendly building materials with effective insulation properties in Southern Algeria, a region increasingly affected by extreme natural phenomena such as intense heat. By exploring the
Mokhtar Rachedi, Abdelouahed Kriker
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Anomalous Increase in Specific Heat of Binary Molten Salt-Based Graphite Nanofluids for Thermal Energy Storage

Applied Sciences, 2018
An anomalous increase of the specific heat was experimentally observed in molten salt nanofluids using a differential scanning calorimeter. Binary carbonate molten salt mixtures were used as a base fluid, and the base salts were doped with graphite ...
Hyun Jung Kim, Byeongnam Jo
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Refrigerant forced-convection condensation inside horizontal tubes [PDF]

, 1968
High vapor velocity condensation inside a tube was studied theoretically. The heat transfer coefficients were calculated by the momentum and heat transfer analogy.
Bae, S., Bae, Soonhoon, J.S. Maulbetsch, Maulbetsch, John S., S. Bae, Maulbetsch, J.S., W.M. Rohsenow, Rohsenow, Warren M., Rohsenow, W.M.   +8 more
core   +1 more source

Calorímetro de gelo: uma abordagem histórica e experimental para o ensino de química na graduação

Química Nova, 2010
In addition to the usual advantage of an ice calorimeter of being able to measure slow heat changes, the instrument described here is extremely simple to construct and operate.
Guilherme W. Tavares, Alexandre G. S. Prado   +1 more
doaj   +1 more source

Heat Diffusion in High-C_p Nb₃Sn Composite Superconducting Wires

Instruments, 2020
A major focus of Nb3Sn accelerator magnets is on significantly reducing or eliminating their training. Demonstration of an approach to increase the Cp of Nb3Sn magnets using new materials and technologies is very important both for particle accelerators ...
Emanuela Barzi, Fabrizio Berritta, Daniele Turrioni, Alexander V. Zlobin   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source