Results 81 to 90 of about 2,838,113 (300)
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The objective of this study was to investigate the influence of a water vapor injection into the intake port of a small compression ignition engine and analyze the effect of the collisions between the water particles and the injected fuel on combustion ...
Se Hun Min, Hyun Kyu Suh
doaj +1 more source
Reentrant classicality of a damped system
For a free particle, the coupling to its environment can be the relevant mechanism to induce quantum behavior as the temperature is lowered. We study general linear environments with a spectral density proportional to {\omega}^s at low frequencies and ...
Ingold, Gert-Ludwig +2 more
core +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Investigation of Finite-Size 2D Ising Model with a Noisy Matrix of Spin-Spin Interactions
We analyze changes in the thermodynamic properties of a spin system when it passes from the classical two-dimensional Ising model to the spin glass model, where spin-spin interactions are random in their values and signs. Formally, the transition reduces
Boris Kryzhanovsky +2 more
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Specific-heat evidence of the first-order superconducting transition in Sr2RuO4
We investigate the specific heat of ultra-pure single crystals of Sr2RuO4, a leading candidate of a spin-triplet superconductor. We for the first time obtained specific-heat evidence of the first-order superconducting transition below 0.8 K, namely ...
Kajikawa, Tomohiro +2 more
core +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Moisture content modelling of thermal properties of persimmon (cv. 'Kaki')
Persimmon is one of the tasty and sweet fruits with short shelf life. Thermal conductivity, thermal diffusivity and specific heat are necessary for storage, drying, packaging and designing of distillation machines.
Somaye Akbari, Reza Amiri Chayjan
doaj +1 more source
Specific heat behavior of high temperature superconductors in the pseudogap regime
Experimental data obtained from thermodynamic measurements in underdoped high temperature superconductors show unusual anomalies in the temperature dependence of the electronic specific heat both in the normal state and at the critical point associated ...
Moca, C. P., Tifrea, I.
core +2 more sources

