Results 91 to 100 of about 7,347,069 (300)

Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective The NeuroPace responsive neurostimulation (RNS) System effectively treats focal drug‐resistant epilepsy (DRE) in adults but lacks pediatric regulatory approval. Despite effective off‐label pediatric use, systemic device‐trial challenges have impeded label expansion.
Mira C. Hasner, Faith C. Robertson, Nathaniel D. Sisterson, Gabriel Lazaro‐Munoz, Florence T. Bourgeois, James W. Wheless, Steven M. Wolf, Peter C. Warnke, Saadi Ghatan, Joffre Olaya, Catherine J. Chu, Brian N. Lundstrom, Sanjeev V. Kothare, Marytery Fajardo, Marike L. D. Broekman, R. Mark Richardson   +15 more
wiley   +1 more source

Detection of specific IgE antibodies in parasite diseases

Brazilian Journal of Medical and Biological Research, 1999
Activation of Th1 or Th2 cells is associated with production of specific immunoglobulin isotypes, offering the opportunity to use antibody measurement for evaluation of T cell function.
M.L.B. Souza-Atta, M.I. Araújo, A. D'Oliveira Júnior, A. Ribeiro-de-Jesus, R.P. Almeida, A.M. Atta, E.M. Carvalho   +6 more
doaj   +1 more source

Methods to Detect MHC-Specific IgE in Mice and Men

Frontiers in Immunology, 2020
Humoral immunity is a major barrier limiting long-term outcome after organ transplantation. Especially, the production of antibodies directed against donor HLA/MHC antigens (i.e.
Anna Marianne Weijler, Jasmin Mucha, Andreas Michael Farkas, Ulrike Baranyi, Nina Pilat, Ara Cho, Ara Cho, Moritz Muckenhuber, Stefan Hopf, Markus Wahrmann, Birgit Linhart, Rudolf Valenta, Rudolf Valenta, Rudolf Valenta, Rudolf Valenta, Thomas Wekerle   +15 more
doaj   +1 more source

Detection of Allergen-Specific IgE Antibody Responses

Journal of Immunotoxicology, 2005
Allergen-specific IgE production is the central event in the pathogenesis of atopic disorders and increases in specific IgE serum antibodies are an indicator of immediate hypersensitivity responses in humans and in animal models of allergy. Consequently, accurate and user-friendly methods are needed to measure serum levels of allergen-specific IgE ...
Wachholz, Petra A., Dearman, Rebecca J., Kimber, Ian   +2 more
openaire   +3 more sources

Omalizumab: clinical use for the management of asthma [PDF]

, 2012
Omalizumab, a humanized monoclonal antibody that binds circulating IgE antibody, is a treatment option for patients with moderate to severe allergic asthma whose asthma is poorly controlled with inhaled corticosteroids and inhaled long-acting ß2 agonist ...
Rekha Chaudhuri, Neil C. Thomson, Thomson, N.C., Chaudhuri, R.   +3 more
core   +1 more source

Semiology of functional/dissociative seizures in idiopathic generalized epilepsy: An inpatient video‐electroencephalographic study

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to estimate the prevalence and characterize the semiology of co‐occurring functional/dissociative seizures (FDSs) and identify clinical features potentially associated with the development of video‐electroencephalography (video‐EEG)‐diagnosed FDSs in patients with idiopathic generalized epilepsy (IGE ...
Javier Peña‐Ceballos, Kishen Radhakrishna, Tenzin Choekyi, Clodagh O'Keeffe, Mohamed Ali, Alma O'Donnell, Tudor Munteanu, Patrick B. Moloney, Hany El Naggar, Gerard Mullins, Peter Widdess‐Walsh, Ronan D. Kilbride, Norman Delanty, Nuala McNicholas   +13 more
wiley   +1 more source

Does age influence diagnostic outcomes in an adult cohort referred to a first‐seizure clinic?

Epilepsia, EarlyView.
Abstract Objective The aging Danish population is associated with increasing morbidity and healthcare utilization. This study examines age‐related differences in resource utilization and diagnostic outcomes between older (65–95 years) and younger adults (18–64 years) evaluated for suspected epilepsy, including clinical management, diagnostic yield, and
Anne Line Lund Birkmose, Corinna Lackmann, Lars Hageman Pinborg, Kimmo Jensen   +3 more
wiley   +1 more source

Measurement of Japanese Cedar Pollen-Specific IgE in Nasal Secretions

Allergology International, 2014
Background: : Japanese cedar pollen (JCP) is the most common allergen for seasonal allergic rhinitis in Japan. Little is known about local production of immunoglobulin (Ig)E in people with or without Japanese cedar pollinosis. The aims of this study were
Hiroshi Sakaida, Sawako Masuda, Kazuhiko Takeuchi   +2 more
doaj   +1 more source

Effect of urban vs. rural residence on the association between atopy and wheeze in Latin America: findings from a case-control analysis. [PDF]

, 2014
BACKGROUND: The association between atopy and asthma is attenuated in non-affluent populations, an effect that may be explained by childhood infections such as geohelminths.
Platts-Mills, TA, Vaca, M., Workman, L, Platts-Mills, T. A. E., Workman, L., Rodrigues, LC, Vaca, M, Chico, ME, Platts-Mills, TAE, Cooper, P. J., Barreto, ML, Barreto, Maurício Lima, Chico, M. E., Endara, P, Cooper, PJ, Endara, P., Rodrigues, Laura Cunha, Cooper, Philip John   +17 more
core   +1 more source

Altered cortical synchronization in photosensitive idiopathic generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto, Cecilia Steinwurzel, Francesco Turco, Enrica Bonanni, Roberto Cantello, Gionata Strigaro   +5 more
wiley   +1 more source