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Approaches to allergy detection using aptasensors [PDF]
1. Immunoglobulins and IgE Antibodies are glycoprotein molecules which are produced by plasma cells in response to an immunogen (1). They belong to a class of spherical proteins called globulins and are hence known as immunoglobulins (Igs).
Mascini, Marco +4 more
core +7 more sources
The sensitivity of ALEX2 Allergy Explorer test in patients suffering from atopic dermatitis and clinical reactions to fish/shrimps was evaluated. We compared the results of specific IgE to allergen reagents (molecular components) and clinical reactions ...
J. Čelakovská +4 more
doaj +1 more source
The study focused on spontaneous and allergen-induced basophil activation (BAT) as well as on specific IgE indicators to major meadow grass pollen allergens on the background of allergen-immunotherapy (AIT) in patients sensitized to weed pollen.
L. Yu. Barycheva +2 more
doaj +1 more source
IgE glycans promote anti-IgE IgG autoantibodies that facilitate IgE serum clearance via Fc Receptors [PDF]
BACKGROUND: Recent studies have shown that IgE glycosylation significantly impacts the ability of IgE to bind to its high-affinity receptor FcεRI and exert effector functions.
Bachmann, Martin F. +6 more
core +2 more sources
IgE antibodies are likely involved in host protection. Trichinella spiralis is a helminth that induces protection through IgE antibodies. The present study examined T.
Naohiro Watanabe
doaj +1 more source
Specific IgE response in patients with brucellosis [PDF]
SUMMARYIn the search to find discriminative serological markers to differentiate between patients with acute brucellosis and those with chronic brucellosis, an enzyme-linked immunosorbent assay (ELISA) was used to determine and compare the brucella-specific IgE response in 80 sera from patients with acute brucellosis, 37 sera from patients with chronic
G F, Araj +3 more
openaire +2 more sources
Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus [PDF]
High levels of serum IgE are considered markers of parasite and helminth exposure. In addition, they are associated with allergic disorders, play a key role in anti-tumoral defence, and are crucial mediators of autoimmune diseases.
Wichmann, H. -Erich +127 more
core +1 more source
Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: peach Pru p 3 allergen as a model. [PDF]
Lipid transfer proteins (LTPs) are the major allergens of Rosaceae fruits in the Mediterranean area. Pru p 3, the LTP and major allergen of peach, is a suitable model for studying food allergy and amino acid sequences related with its IgE-binding ...
Tordesillas Villuendas, Leticia +7 more
core +1 more source
Environmental determinants of total IgE among school children living in the rural Tropics: importance of geohelminth infections and effect of anthelmintic treatment. [PDF]
BACKGROUND: The environmental factors that determine the elevated levels of polyclonal IgE observed in populations living in the Tropics are poorly understood but may include geohelminth infections.
Cooper Philip J +27 more
core +1 more source
HELMINTH-SPECIFIC IgE AND EXTRINSIC ALLERGEN-SPECIFIC IgE IN PATIENTS WITH ATOPIC DISEASES.
ABSTRACT To investigate the role of helminth-induced IgE in the worm-atopy relationship, the levels of IgE directed against helminthic antigens (Ascaris, Echinococcus, and Schistosoma)and total IgE...
Jawad K. A. Al-Diwan +3 more
openaire +1 more source

