Results 41 to 50 of about 516,930 (293)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evaluation of Liquid Hydrogen/Hydrogen Peroxide Propellant Combination for Advanced Launch Vehicle Upper Stage

open access: yesAerospace
Hydrogen peroxide (H2O2) is a dense, storable oxidizer, but its suitability for high-energy upper stages is limited. This study evaluates liquid hydrogen–hydrogen peroxide (LH2/H2O2) as an alternate propellant using KSLV-II as the reference vehicle ...
Min-Seon Jo, Jeong-Yeol Choi
doaj   +1 more source

Interferometric method for specific impulse determination

open access: yesOptical Engineering, 2018
One of the main figures of merit in laser-ablative propulsion is the specific impulse, Isp, defined as the impulse per unit weight of fuel, and it is related to the exhaust velocity, ve, by the acceleration of gravity, Isp  =  ve  /  g. Being a key magnitude, Isp needs to be accurately determined. It is usually inferred from other measurable quantities:
Toro Salazar, Cinthya Emma   +2 more
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Experimental Study on the Propulsion Performance of Laser Ablation Induced Pulsed Plasma

open access: yesAerospace
This study investigates the influence of electromagnetic fields on the propulsion performance of laser plasma propulsion. Based on the principle of pulsed plasma thrusters, an electromagnetic field is utilized to accelerate laser plasma, achieving ...
Hang Song   +4 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Ground and flight tests of AlSat-1B butane propulsion system

open access: yesPropulsion and Power Research, 2022
On September 26, 2016 Algerian Space Agency launched AlSat-1B, the second in a series of medium resolution earth observation satellites mission. AlSat-1B electro-thermal propulsion system follows the classic design principle that has been used on ...
D. Darfilal, D. Gibbon
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Comparative results of computational and theoretical study of the annular nozzle with a flat central body

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение
One of the ways to improve specific characteristics of the power plant of a launch vehicle for ladeploying payload to the near-Earth space is to provide the possibility of operation of a fixed nozzle in the design mode over the whole active leg of the ...
A. A. Kirshina   +2 more
doaj   +1 more source

Effect of Combustion Chamber Geometrical Parameters on the Decomposition and Combustion Characteristics of an ADN-Based Thruster

open access: yesMicromachines, 2022
In this paper, numerical simulations were used to study the decomposition and combustion processes inside the 0.2 N-class ADN-based thruster, and the effects of two geometrical parameters (length and diameter) of the combustion chamber on the combustion ...
Yangyang Hou   +3 more
doaj   +1 more source

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