Results 11 to 20 of about 115,986 (250)

Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype

open access: yesNature Communications
Conventional laboratory mice housed under specific pathogen-free (SPF) conditions are the standard model in biomedical research. However, in recent years, many rodent-based studies have been deemed irreproducible, raising questions about the suitability ...
Solveig Runge   +15 more
doaj   +2 more sources

Microbial communities and substrate properties influence the fate of a human pathogen in horticultural substrates with different peat content

open access: yesFrontiers in Horticulture
The use of peat alternatives in horticulture is part of an important strategy aiming at the reduction of CO2 emission and the preservation of natural wetlands.
Antje Müller   +4 more
doaj   +2 more sources

Distributable, metabolic PET reporting of tuberculosis

open access: yesNature Communications
Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum which limits sampling to ...
R. M. Naseer Khan   +29 more
doaj   +2 more sources

Nonylphenol exposure increases the risk of Hirschsprung’s disease by inducing macrophage M1 polarization

open access: yesEcotoxicology and Environmental Safety
Nonylphenol (NP), a ubiquitous environmental contaminant used as a surfactant in industrial production and classified as an endocrine disruptor, could interfere hormone secretion and exhibit neurotoxicity in organisms.
Xuefeng Yang   +7 more
doaj   +2 more sources

Soil-free bioassays for testing novel control agents against Phytophthora cinnamomi root rot

open access: yesFrontiers in Plant Science
Phytophthora cinnamomi is considered as one of the world’s worst plant pathogens, infecting about 5,000 plant species including those of agricultural and environmental significance.
Leny Jane Pame   +7 more
doaj   +2 more sources

Detoxification of Ustiloxin A Through Oxidative Deamination and Decarboxylation by Endophytic Fungus Petriella setifera

open access: yesToxins
Ustiloxins are a group of cyclopeptide mycotoxins produced by rice false smut pathogen Villosiclava virens (anamorph: Ustilaginoidea virens) which seriously threaten the safety production of rice and the health of humans and livestock.
Peng Li   +8 more
doaj   +2 more sources

Are there advantages in the use of specific pathogen‐free baboons in pig organ xenotransplantation models? [PDF]

open access: yesXenotransplantation, 2014
AbstractBaboons have natural antibodies against pig antigens. We have investigated whether there are differences in anti‐non‐Gal pig antibody levels between baboons maintained under specific pathogen‐free (SPF) conditions and those housed under conventional conditions (non‐SPF) that might be associated with improved outcome after pig‐to‐baboon organ ...
Huidong, Zhou   +7 more
openaire   +2 more sources

Development and maintenance of a specific pathogen free (SPF) zebrafish research facility for Pseudoloma neurophilia

open access: yesDiseases of Aquatic Organisms, 2011
Pseudoloma neurophilia (Microsporidia) is very common in zebrafish research facilities. A new zebrafish facility was established at the Sinnhuber Aquatic Resource Laboratory (SARL) at Oregon State University, and thus we used this as an opportunity to ...
M. Kent   +6 more
semanticscholar   +1 more source

Bacterial Composition and Metabolomics of Dental Plaque From Adolescents

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Supragingival dental plaque samples were collected from 40 Swedish adolescents, including 20 with caries lesions (CAR) and 20 caries-free (CF). Fresh plaque samples were subjected to an ex vivo acid tolerance (AT) test where the proportion of bacteria ...
Kristian Havsed   +15 more
doaj   +1 more source

UltraSEQ, a Universal Bioinformatic Platform for Information-Based Clinical Metagenomics and Beyond

open access: yesMicrobiology Spectrum, 2023
Applied metagenomics is a powerful emerging capability enabling the untargeted detection of pathogens, and its application in clinical diagnostics promises to alleviate the limitations of current targeted assays.
Bryan T. Gemler   +8 more
doaj   +1 more source

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