Results 81 to 90 of about 338,311 (289)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Frontiers in Plant ScienceFibrous and pioneer roots are essential in the uptake and transport of water and nutrients from the soil. Their dynamic may be influenced by the changing of soil physicochemical properties due to the addition of biochar, which, in turn, has been shown to
Peter Beatrice +7 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2009 It is generally considered that root turnover is a major contributor to organic matter and mineral nutrient cycles in organic managed agroecosystems. Approach: This study designed to investigate whether microbial activity could affect on root properties ...
Pietsch, Gabriele +4 more
core
, 2014 The functional traits and biomass allocations of aquatic (A) and terrestrial (T) reed (a, specific leaf area (SLA); b, specific root length (SRL); c, mean root area of unit mass (Rarea); d, mean root diameter (Rdiam); e, Root:Shoot ratio (RS); f, root ...
Chengjun Ji (524320) +9 more
core +1 more source
Root respiration and other four classical root traits
, 2020 This dataset is relevant to species specific root respiration and other four classical root traits (root N concentration, root diameter, root tissue density and specific root length).We aim to explore the relationships between root respiration and other ...
Mengguang Han (9472442)
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
, 2011 SPACSYS, a model of C and N cycling in the soil–plant–atmosphere continuum that incorporates a detailed three-dimensional root growth sub-model, was tested for its ability to predict the growth and root length density (RLD) distribution of winter wheat ...
Ian J. Bingham +5 more
core +1 more source
Validation of Kvaal's and Cameriere's methods of age estimation in people of Marathwada origin
CHRISMED Journal of Health and Research, 2017 Context: Aging, in forensic context, is necessary both for the dead and the living. Kvaal et al. introduced a method of age estimation by indirectly measuring secondary dentin deposition on radiographs.
Maneesha Das +6 more
doaj +1 more source