Results 111 to 120 of about 639,528 (302)
Праці Інституту електродинаміки Національної академії наук УкраїниThe paper is devoted to the analysis of frequency requirements regulated by the national and international standards for distribution networks and microgrids.
А.О. Стелюк +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
UML specification of distributed system environments [PDF]
, 1999 The specification of distributed systems is a complex task, which is made easier by the use of object-oriented design methodologies. With the advent of UML as a standard notation for object-oriented software design, the application of this notation to ...
Waters, A. Gill, Akehurst, David H.
core
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Analysis, specification and verification requirements for control systems cloud training platforms
CTE Workshop Proceedings, 2014 Digital control systems are now an essential and critical part of Cloud Training Platforms. Numerous methods, tools and standards have been developed to ensure that such systems will comply with their requirements.
Elvira Faridovna Matveeva +5 more
doaj +1 more source
The formal specification of a blackboard framework [PDF]
The blackboard architecture is a complex, though powerful, model of problem-solving, and opinions vary as to its interpretation. The use of formal specifications for blackboard systems appears warranted by their complexity, their application in real-time
Craig, Iain D.
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Towards GCM re-configuration – extending specification by norm
, 2008 We continue investigation of formal specification of Grid Component systems by temporal logics and subsequent application of temporal resolution as a verification technique.
Basso, A., Bolotov, A.
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source