Results 101 to 110 of about 639,528 (302)

Interpretation of Specification for Developing Clinical Practice Guidelines of Organic Integration of Traditional Chinese and Western Medicine [PDF]

open access: yesYixue xinzhi zazhi
In recent years, the number of clinical practice guidelines for the integration of traditional Chinese medicine (TCM) and western medicine(WM) has been increasing year by year. However, there are obvious problems of "knot without compatibility".
JIN Yinghui   +12 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Specific and Non-Specific Immunosuppression in Chickens

open access: yesPoultry Science, 1975
Specific immunosuppression, caused by the passive transfer of immune sera, and non-specific immunosuppression, caused by ACTH, were investigated for possible interactions. The data confirm earlier studies which show that both types of suppression when administered independently cause reductions in humoral immune responsiveness.
P, Thaxton, P S, Young
openaire   +2 more sources

dcosme/specification-curves

open access: yes, 2019
<p>Tutorial on Specification Curve Analysis as presented at Flux 2019.</p ...
Danielle Cosme, Danielle Cosme (699818)
core   +1 more source

An ANOVA method of evaluating the specification uncertainty in roughness measurement [PDF]

open access: yes, 2015
The specifications of roughness used in industry are normally incomplete, and the incompleteness can induce a significant uncertainty, called specification uncertainty.
Ding, Hao   +3 more
core   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Development of Specification for Dynamic Performance Assessment and Testing Verification of Rolling Stock

open access: yes机车电传动, 2020
The development background and main technical contents of the national standard GB/T 5599—2019 "Specification for Dynamic Performance Assessment and Testing Verification of Rolling Stock" was introduced, focusing on the development of parameter related ...
Li XU, Chunshuang NI, Meng CHEN, Wei WU
doaj  

Generation of germ cells from pluripotent stem cells in mammals

open access: yesReproductive Medicine and Biology, 2018
Background The germ cell lineage transmits genetic and epigenetic information to the next generation. Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been studied extensively. Recently, in vitro models of PGC induction
Masafumi Hayashi   +3 more
doaj   +1 more source

IMS Learning Design Version 1.0 Final Specification

open access: yes, 2006
The IMS Learning Design specification supports the use of a wide range of pedagogies in online learning. Rather than attempting to capture the specifics of many pedagogies, it does this by providing a generic and flexible language.
Hummel, Hans   +6 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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