Results 81 to 90 of about 282,705 (268)
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
This paper gives an informal presentation of the language currently used at the Programming Research Group. Oxford University for documenting the specification and the design of computer systems. The language is an extension of conventional set theoretical notation.
openaire +2 more sources
The development background and main technical contents of the national standard GB/T 5599—2019 "Specification for Dynamic Performance Assessment and Testing Verification of Rolling Stock" was introduced, focusing on the development of parameter related ...
Li XU, Chunshuang NI, Meng CHEN, Wei WU
doaj
Generation of germ cells from pluripotent stem cells in mammals
Background The germ cell lineage transmits genetic and epigenetic information to the next generation. Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been studied extensively. Recently, in vitro models of PGC induction
Masafumi Hayashi +3 more
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
The paper is devoted to the analysis of frequency requirements regulated by the national and international standards for distribution networks and microgrids.
А.О. Стелюк +1 more
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Analysis, specification and verification requirements for control systems cloud training platforms
Digital control systems are now an essential and critical part of Cloud Training Platforms. Numerous methods, tools and standards have been developed to ensure that such systems will comply with their requirements.
Elvira Faridovna Matveeva +5 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

