Results 81 to 90 of about 282,705 (268)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A specification language

open access: yes, 1982
This paper gives an informal presentation of the language currently used at the Programming Research Group. Oxford University for documenting the specification and the design of computer systems. The language is an extension of conventional set theoretical notation.
openaire   +2 more sources

Development of Specification for Dynamic Performance Assessment and Testing Verification of Rolling Stock

open access: yes机车电传动, 2020
The development background and main technical contents of the national standard GB/T 5599—2019 "Specification for Dynamic Performance Assessment and Testing Verification of Rolling Stock" was introduced, focusing on the development of parameter related ...
Li XU, Chunshuang NI, Meng CHEN, Wei WU
doaj  

Generation of germ cells from pluripotent stem cells in mammals

open access: yesReproductive Medicine and Biology, 2018
Background The germ cell lineage transmits genetic and epigenetic information to the next generation. Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been studied extensively. Recently, in vitro models of PGC induction
Masafumi Hayashi   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

АНАЛІЗ ВИМОГ ЗА ЧАСТОТОЮ, ЩО РЕГЛАМЕНТУЮТЬСЯ НАЦІОНАЛЬНИМИ ТА МІЖНАРОДНИМИ СТАНДАРТАМИ ДЛЯ РОЗПОДІЛЬЧИХ МЕРЕЖ І МІКРОМЕРЕЖ

open access: yesПраці Інституту електродинаміки Національної академії наук України
The paper is devoted to the analysis of frequency requirements regulated by the national and international standards for distribution networks and microgrids.
А.О. Стелюк   +1 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Analysis, specification and verification requirements for control systems cloud training platforms

open access: yesCTE Workshop Proceedings, 2014
Digital control systems are now an essential and critical part of Cloud Training Platforms. Numerous methods, tools and standards have been developed to ensure that such systems will comply with their requirements.
Elvira Faridovna Matveeva   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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