Results 121 to 130 of about 4,678,205 (343)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Positron emission tomography (PET) and magnetic resonance imaging (MRI) for the assessment of axillary lymph node metastases in early breast cancer: systematic review and economic evaluation

open access: yesHealth Technology Assessment, 2011
Background: Breast cancer is the most common type of cancer in women. Evaluation of axillary lymph node metastases is important for breast cancer staging and treatment planning.
KL Cooper   +9 more
doaj   +1 more source

Preliminary study on the diagnostic value of urine cell glucose metabolism detection for male urothelial carcinoma [PDF]

open access: yesJournal of Men's Health
This study assessed the potential of urine abnormal glycolytic metabolism detection versus urine cytology in diagnosing male urothelial carcinoma, using pathological results as the gold standard.
Yaoyao Wu   +5 more
doaj   +1 more source

RNA Binding: Getting Specific about Specificity [PDF]

open access: yesCell Chemical Biology, 2016
Sequence-specific nucleic acid binding proteins do not recognize one sequence out of all possibilities; rather, they bind to many sequences with a range of affinities. In this issue of Cell Chemical Biology, Lin et al. (2016), describe the entire landscape of affinities between different RNA molecules and an RNA-binding protein, thus providing a ...
openaire   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Acupuncture: Specific and Non-Specific Effects [PDF]

open access: yesForschende Komplementärmedizin / Research in Complementary Medicine, 2008
As an alternative and complement to conventional or allopathic medicine, acupuncture has become a firmly established therapy in many countries. Despite this wide acceptance, the question of how acupuncture works, or whether it works at all, remains the subject of lively debate. One problem in the discussion of acupuncture and its possible mechanisms is
openaire   +2 more sources

Interspecies reactivity and intraspecies specificity of antilymphoid globulin [PDF]

open access: yes, 1967
Horse antihuman and antidog antilymphocyte globulins were shown to possess leukoagglutinating antibodies when tested against the white cells from a number of other divergent species.
Iwasaki, Y   +5 more
core  

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

The Non-Specific Drp1 Inhibitor Mdivi-1 Has Modest Biochemical Antioxidant Activity [PDF]

open access: gold, 2022
Evan A. Bordt   +3 more
openalex   +1 more source

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