Results 211 to 220 of about 2,598,347 (318)

Diagnostic accuracy of non-culture methods for the diagnosis of melioidosis: a systematic review and meta-analysis. [PDF]

BMC Infect Dis
Chen C, Fang J, Li X, Rajaofera MJN, Zhang N, Zhang Y, Xia Q.   +6 more
europepmc   +1 more source

Constants of the quartz-wedge saccharimeter and the specific rotation of sucrose. I. The constants for the 26-gram normal weight

, 1916
Frank S. Bates, Richard F. W. Jackson
openalex   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Cas12a Cis-cleavage mediated lateral flow assay enables multiplex and ultra-specific nucleic acid detection. [PDF]

Nat Commun
Lin M, Qiu Z, Hao M, Qi W, Zhang T, Shen Y, Xiao H, Liang C, Xie L, Jiang Y, Cheng M, Tian T, Zhou X.   +12 more
europepmc   +1 more source

ON THE FORMATION OF SPECIFIC PROTEOLYTIC FERMENTS IN RESPONSE TO THE PARENTERAL INTRODUCTION OF FOREIGN PROTEIN

, 1915
Alonzo Englebert Taylor, Florence Hulton
openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

A multicentre comparative study of serological methods for diagnosing Chagas disease in Brazil. [PDF]

Mem Inst Oswaldo Cruz
Ostermayer AL, Medeiros FAC, Iturra JAD, de Souza Filho JA, Leony LM, Vasconcelos LCM, Siriano LDR, Tavares SBDN, Belo VS, de Sousa AS, Santos FLN.   +10 more
europepmc   +1 more source

Specificities of lipases

Journal of Lipid Research, 1963
P. Savary, P. Desnuelle
openaire   +4 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Dissecting crosstalk induced by cell-cell communication using single-cell transcriptomic data. [PDF]

Nat Commun
Hou J, Zhao W, Nie Q.
europepmc   +1 more source