Results 241 to 250 of about 2,010,640 (293)

MIF as an oncogenic driver of low‐heterogeneity melanomas

Molecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran, Gabriela Athziri Sánchez‐Zuno, Rajan P. Kulkarni, Harriet M. Kluger, Richard Bucala   +4 more
wiley   +1 more source

Use of a Miniaturized Near-Infrared Spectroscopy Device for Type 2 Diabetes Mellitus Screening: Pooled Analysis of the Pilot ANODE01 and ANODE02 Studies. [PDF]

J Diabetes Sci Technol
Choudhary P, Paldánius PM, Salter JE, Lazaro-Pacheco D, Cos Claramunt FX.   +4 more
europepmc   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

The diagnostic role of FNA based on clinicopathological features in thyroid malignancy. [PDF]

BMC Endocr Disord
Fallahi MM, Koulaian S, Mardani P, Malekhosseini SA, Shahriarirad R.   +4 more
europepmc   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Development of a Novel Nested-RT-LAMP Assay for the Rapid and Accurate Coronavirus Disease-2019 Diagnosis. [PDF]

Can J Infect Dis Med Microbiol
Mirzaei H, Sepahi N, Ghasemian A, Ranjbar R, Samsami S, Mansoori Y, Chenari M, Montaseri Z, Namavari N, Namavari S, Ghanbariasad A.   +10 more
europepmc   +1 more source

Diagnostic accuracy of screening and diagnostic tests used in a state-wide tuberculosis prevalence survey in India. [PDF]

Sci Rep
Giridharan P, Inbaraj LR, Frederick A, Selvaraju S, Ramraj B, Thiruvengadam K, Daniel BD, Padmapriyadarsini C.   +7 more
europepmc   +1 more source

Artificial Intelligence Models Accuracy for Odontogenic Keratocyst Detection From Panoramic View Radiographs: A Systematic Review and Meta-Analysis. [PDF]

Health Sci Rep
Shoorgashti R, Alimohammadi M, Baghizadeh S, Radmard B, Ebrahimi H, Lesan S.   +5 more
europepmc   +1 more source

The diagnostic accuracy of blood C-reactive protein and erythrocyte sedimentation rate in periprosthetic joint infections - A 10-year analysis of 1510 revision hip and knee arthroplasties from a single orthopaedic center. [PDF]

J Orthop Surg Res
Grzelecki D, Kocon M, Mazur R, Grajek A, Kowalczewski J.   +4 more
europepmc   +1 more source

Development and evaluation of fluorescent recombinase polymerase amplification (RPA)-based method for rapid detection of Necator americanus. [PDF]

PLoS Negl Trop Dis
Liang JR, Yan SN, Yang HY, Yang S, Shen YJ, Huo LL, Cai YC, Mo ZR, Zheng B, Xu B, Hu W.   +10 more
europepmc   +1 more source