Results 21 to 30 of about 1,989,066 (249)

Alix: A Candidate Serum Biomarker of Alzheimer’s Disease

Frontiers in Aging Neuroscience, 2021
Alzheimer’s disease (AD) is the most common fatal neurodegenerative disease of the elderly worldwide. The identification of AD biomarkers will allow for earlier diagnosis and thus earlier intervention.
Yingni Sun, Yingni Sun, Jin Hua, Gen Chen, Jianjie Li, Jiateng Yang, Hongwei Gao   +6 more
doaj   +1 more source

Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library

eLife, 2020
Protein-protein interaction specificity is often encoded at the primary sequence level. However, the contributions of individual residues to specificity are usually poorly understood and often obscured by mutational robustness, sequence degeneracy, and ...
Thuy-Lan V Lite, Robert A Grant, Isabel Nocedal, Megan L Littlehale, Monica S Guo, Michael T Laub   +5 more
doaj   +1 more source

Metabolic syndrome: Performance of five different diagnostic criterias

Indian Journal of Endocrinology and Metabolism, 2014
Background: The aim of this study is to describe the metabolic syndrome (MS) and to evaluate five diagnostic criteria of the MS with respect to their sensitivity and specificity in patients with type 2 diabetes mellitus (T2DM).
S Ogedengbe Onesi, U Ezeani Ignatius
doaj   +1 more source

Sodium butyrate attenuates oxidative stress, apoptosis, and excessive mitophagy in sodium fluoride-induced hepatotoxicity in rats

Ecotoxicology and Environmental Safety
Aim: Long-term exposure to excess sodium fluoride (NaF) can cause chronic fluorosis. Liver, the most important detoxification organ, is the most vulnerable to the effects of fluoride.
Jing Xia, Xiaolin Zhang, Leiyu Xu, Nan Yan, Zhenxiang Sun, Xiaoxu Duan, Lu Meng, Rong Qi, Fu Ren, Zhengdong Wang   +9 more
doaj   +1 more source

Image specificity

2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), 2015
For some images, descriptions written by multiple people are consistent with each other. But for other images, descriptions across people vary considerably. In other words, some images are specific $-$ they elicit consistent descriptions from different people $-$ while other images are ambiguous.
Parikh, Devi, Jas, Mainak
openaire   +4 more sources

A decade of progress in understanding LRRTM and Slitrk synaptic cell-adhesion molecules

Molecules and Cells
: For over a decade, synaptic cell-adhesion molecules (CAMs) have been recognized as fundamental determinants of neural circuit specificity and diversity.
Dongwook Kim, Byeongchan Kim, Ji Won Um, Jaewon Ko   +3 more
doaj   +1 more source

Comparison of Three Real-Time PCR Assays Targeting the SSU rRNA Gene, the COWP Gene and the DnaJ-Like Protein Gene for the Diagnosis of Cryptosporidium spp. in Stool Samples

Pathogens, 2021
As qualified microscopy of enteric parasitoses as defined by high diagnostic accuracy is difficult to maintain in non-endemic areas due to scarce opportunities for practicing with positive sample materials, molecular diagnostic options provide less ...
Felix Weinreich, Andreas Hahn, Kirsten Alexandra Eberhardt, Torsten Feldt, Fred Stephen Sarfo, Veronica Di Cristanziano, Hagen Frickmann, Ulrike Loderstädt   +7 more
doaj   +1 more source

Multisite Validation of Cryptococcal Antigen Lateral Flow Assay and Quantification by Laser Thermal Contrast

Emerging Infectious Diseases, 2014
Cryptococcal meningitis is common in sub-Saharan Africa. Given the need for data for a rapid, point-of-care cryptococcal antigen (CRAG) lateral flow immunochromatographic assay (LFA), we assessed diagnostic performance of cerebrospinal fluid (CSF ...
David R. Boulware, Melissa A. Rolfes, Radha Rajasingham, Maximilian von Hohenberg, Zhenpeng Qin, Kabanda Taseera, Charlotte Schutz, Richard Kwizera, Elissa K. Butler, Graeme Meintjes, Conrad Muzoora, John C. Bischof, David B. Meya   +12 more
doaj   +1 more source

Validation of the Use of Dried Blood Samples for the Detection of Toxoplasma gondii Antibodies in Stray Cats (Felis s. catus)

Pathogens, 2021
If validated beforehand, the analysis of dried blood on blotting paper (BP samples) is very useful for monitoring free-ranging animals. We aimed to validate this method for the detection of antibodies against Toxoplasma gondii in stray cats.
Julie Alice Simon, Dominique Aubert, Régine Geers, Isabelle Villena, Marie-Lazarine Poulle   +4 more
doaj   +1 more source

Validation of a Commercial Loop-Mediated Isothermal Amplification (LAMP)-Based Kit for the Detection of Salmonella spp. According to ISO 16140:2016

Applied Sciences, 2021
The traditional cultural method (PCR and Real-Time PCR) for Salmonella spp. detection and identification is laborious and time-consuming. A qualitative LAMP method detecting Salmonella spp. was validated in compliance with ISO 16140:2016.
Calogero Di Bella, Antonella Costa, Sonia Sciortino, Giuseppa Oliveri, Gaetano Cammilleri, Francesco Geraci, Daniela Lo Monaco, Davide Carpintieri, Giuseppe Lo Bue, Carmelo Bongiorno, Alessandro Altomare, Valentina Ciprì, Rosario Pitti, Carmine Lanzillo, Giuseppe Arcoleo, Rosalinda Allegro   +15 more
doaj   +1 more source