Results 41 to 50 of about 2,080,270 (249)

Regulation of 11β-HSD1 reductase and the HPA axis by long-snake moxibustion in kidney-yang deficiency rats

Heliyon
Background: Long-snake moxibustion can improve hypothalamic-pituitary-adrenal (HPA) axis function in patients with kidney-yang deficiency (KYDS). 11β-HSD1 controls the HPA axis by boosting CORT production via reductase activity.
Hui Huang, Jingjiao Zeng, Limei Tang, Lele Geng, Xijing Yu, Chenying Deng, Hang Liu, Ping Huang, Ensi Hong, Xiuwu Hu   +9 more
doaj   +1 more source

An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases

eLife, 2014
Malate and lactate dehydrogenases (MDH and LDH) are homologous, core metabolic enzymes that share a fold and catalytic mechanism yet possess strict specificity for their substrates.
Jeffrey I Boucher, Joseph R Jacobowitz, Brian C Beckett, Scott Classen, Douglas L Theobald   +4 more
doaj   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions

Cell Reports
Summary: Neuroinflammation is a well-established risk factor for various neurological disorders and cognitive decline. However, the precise molecular mechanisms linking inflammation with neuropsychiatric symptoms remain unclear.
Hyeji Jung, Byeongchan Kim, Gyubin Jang, Hyeonho Kim, Ae-Ree Lee, Sung-Hyun Yoon, Kyung-Seo Lee, Gaeun Hyun, Younghye Kim, Jaewon Ko, Je-Wook Yu, Ji Won Um   +11 more
doaj   +1 more source

Bottom-up and top-down influences at untrained conditions determine perceptual learning specificity and transfer

eLife, 2016
Perceptual learning is often orientation and location specific, which may indicate neuronal plasticity in early visual areas. However, learning specificity diminishes with additional exposure of the transfer orientation or location via irrelevant tasks ...
Ying-Zi Xiong, Jun-Yun Zhang, Cong Yu
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Accelerated corrosion behavior of DD32 alloy in the marine atmospheric environment

Journal of Materials Research and Technology
The corrosion of DD32 alloy in a marine atmospheric environment was investigated through accelerated corrosion tests. The corrosion morphology and products of alloy were discussed by the SEM, XRD, and XPS characterization.
Jianglong Ma, Guangming Kong, Zhiguo Liu, Lin Zhao, Ang Tian, Chuangwei Liu, Yiwei Wang   +6 more
doaj   +1 more source

Microscopic examination and smear negative pulmonary tuberculosis in Ethiopia

The Pan African Medical Journal, 2014
BACKGROUND: tuberculosis causes illness among millions of people each year and ranks as the second leading cause of death from infectious disease worldwide.
Tibebeselassie Seyoum Keflie, Gobena Ameni   +1 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Constraints on the position and interpretation of bare singular indefinites in Russian

Linguistica, 2016
In this paper, I discuss the distribution of bare singular indefinite nominals in Russian. I argue that these nominal phrases are full-fledged indefinites and can have both specific and non-specific indefinite interpretations.
Olga Borik
doaj   +1 more source