Results 41 to 50 of about 2,535,115 (299)

Specificity effects with clitic doubling and pe marking [PDF]

Bucharest Working Papers in Linguistics, 2014
This paper focuses on the relationship between pe marking and clitic doubling in Romanian arguing in favour of Bleam’s (1999) hypothesis: the two mechanisms are semantically related through the specificity effects they both engender, but are otherwise ...
Alina-Mihaela Tigău
doaj  

Gene Set Analysis: Challenges, Opportunities, and Future Research

Frontiers in Genetics, 2020
Gene set analysis methods are widely used to provide insight into high-throughput gene expression data. There are many gene set analysis methods available.
Farhad Maleki, Katie Ovens, Daniel J. Hogan, Anthony J. Kusalik   +3 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Spatiotemporal dynamics of benzylisoquinoline alkaloid gene expression and co-expression networks during Papaver Somniferum developmental stages

Scientific Reports
Benzylisoquinoline alkaloids (BIAs) are essential secondary metabolites produced by Papaver somniferum, widely recognized for their pharmaceutical importance.
Zishi Wang, Quanzheng Yun, Jinyuan Hu, Zhen Wei, Deri Feng, Ning Li, He Xu, Lihong Fu, Zhenlong Wang, Shujin Li, Fangru Liu, Yan Wang, Bin Cong, Baishi Wang   +13 more
doaj   +1 more source

The validity of self‐reported cancer in an Australian population study

Australian and New Zealand Journal of Public Health, 2014
Objective: The aim of this study is to determine the validity of self‐reported cancer data by comparing it to the Australian Cancer Database (ACD). Methods: Self‐reported data were obtained from the Australian Diabetes, Obesity and Lifestyle (AusDiab ...
Venurs Loh, Jessica Harding, Vira Koshkina, Elizabeth Barr, Jonathan Shaw, Dianna Magliano   +5 more
doaj   +1 more source

SPECIFICS. [PDF]

The Lancet
n ...
openaire   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1

Nature Communications
The ubiquitin system regulates eukaryotic physiology by modifying myriad substrate proteins. Substrate specificity and the assembly of ubiquitin signals are determined by ubiquitin ligases, some of which also modify non-protein biomolecules.
Barbara Orth, Pavel Pohl, Florian Aust, Yanlong Ji, Ayshwarya Seenivasan, Olexandr Dybkov, Xiaojun Julia Liang, Lars Bock, Florian Leidner, Sophie Levantovsky, Patrick Schardey, Pascal Sander, Nathanael J. Disch, Masanja L. Trautz, Athanasia Mizi, Argyris Papantonis, Christof Lenz, Helmut Grubmüller, Wieland Steinchen, Christian Behrends, Henning Urlaub, Matthias Gehringer, Sonja Lorenz   +22 more
doaj   +1 more source

Regulation of 11β-HSD1 reductase and the HPA axis by long-snake moxibustion in kidney-yang deficiency rats

Heliyon
Background: Long-snake moxibustion can improve hypothalamic-pituitary-adrenal (HPA) axis function in patients with kidney-yang deficiency (KYDS). 11β-HSD1 controls the HPA axis by boosting CORT production via reductase activity.
Hui Huang, Jingjiao Zeng, Limei Tang, Lele Geng, Xijing Yu, Chenying Deng, Hang Liu, Ping Huang, Ensi Hong, Xiuwu Hu   +9 more
doaj   +1 more source

An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases

eLife, 2014
Malate and lactate dehydrogenases (MDH and LDH) are homologous, core metabolic enzymes that share a fold and catalytic mechanism yet possess strict specificity for their substrates.
Jeffrey I Boucher, Joseph R Jacobowitz, Brian C Beckett, Scott Classen, Douglas L Theobald   +4 more
doaj   +1 more source