Results 51 to 60 of about 2,080,270 (249)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Leveraging the crosstalk between cGAS-STING and pyroptosis by nanomedicine to enhance antitumor immunity

Journal of Nanobiotechnology
The cGAS-STING pathway and pyroptosis represent two potent immunostimulatory mechanisms with immense potential for cancer therapy. cGAS-STING activation drives type I interferon production and dendritic cell maturation, while pyroptosis, a form of ...
Yumin Wang, Jinxia Chen, Xuan Zhang, Zhenhua Ji, Na Zhang, Ning Li, Xiu Zhang, Shuang Zhao, Chunfei Li, Kerui Shi, Erdan Wang, Yuzi Jin   +11 more
doaj   +1 more source

Specificity Distinctions

Journal of Semantics, 2001
This paper is concerned with semantic noun phrase typology, focusing on the question of how to draw fine-grained distinctions necessary for an accurate account of natural language phenomena. In the extensive literature on this topic, the most commonly encountered parameters of classification concern the semantic type of the denotation of the noun ...
openaire   +3 more sources

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

The conformation of the nSrc specificity-determining loop in the Src SH3 domain is modulated by a WX conserved sequence motif found in SH3 domains

Frontiers in Molecular Biosciences
Cellular signaling networks are modulated by multiple protein-protein interaction domains that coordinate extracellular inputs and processes to regulate cellular processes. Several of these domains recognize short linear motifs, or SLiMs, which are often
Frederick Longshore-Neate, Caroline Ceravolo, Cole Masuga, Elise F. Tahti, Jadon M. Blount, Sarah N. Smith, Jeanine F. Amacher   +6 more
doaj   +1 more source

Intravital and postmortem diagnostics of myocardial hypertrophy of the left ventricle:identity or convention? [PDF]

Терапевтический архив, 2018
The aim of the study is to assess the compliance of the results of electrocardiographic (ECG) and echocardiographic diagnostic methods of hypertrophy of left ventricular myocardium (LVH) with the postmortem finding of measurement of left ventricular ...
S N Bogomolov, A N Kulikov, J A Tikhonova, V N Solntsev, M G Rybakova, A Y Gudkova, A N Kuchmin   +6 more
doaj   +1 more source

Acupuncture: Specific and Non-Specific Effects [PDF]

Forschende Komplementärmedizin / Research in Complementary Medicine, 2008
As an alternative and complement to conventional or allopathic medicine, acupuncture has become a firmly established therapy in many countries. Despite this wide acceptance, the question of how acupuncture works, or whether it works at all, remains the subject of lively debate. One problem in the discussion of acupuncture and its possible mechanisms is
openaire   +2 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The RNA-binding protein RNP29 is an unusual Toc159 transport substrate

Frontiers in Plant Science, 2014
The precursors of RNP29 and Ferredoxin (Fd2) were previously identified in the cytosol of ppi2 plant cells with their N-terminal amino acid acetylated. Here, we explore whether precursor accumulation in ppi2 is characteristic for Toc159 client proteins ...
Julia eGrimmer, Anja eRödiger, Wolfgang eHoehenwarter, Stefan eHelm, Sacha eBaginsky   +4 more
doaj   +1 more source