Results 21 to 30 of about 2,535,115 (299)

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry [PDF]

, 2014
Deubiquitylases (DUBs) are key regulators of the ubiquitin system which cleave ubiquitin moieties from proteins and polyubiquitin chains. Several DUBs have been implicated in various diseases and are attractive drug targets. We have developed a sensitive
Virdee, Satpal; id_orcid, Gray, Nathanael, Trost, Matthias, Ritorto, Maria Stella, Gray, Nathanael S., Alessi, Dario R., Perez-Oliva, Ana B., Wood, Nicola T., Alessi, Dario R.; id_orcid, Knebel, Axel, Buhrlage, Sara J., Ewan, Richard, Wightman, Melanie, Morrice, Nicholas A., Virdee, Satpal, Kelly, Sharon M.   +15 more
core   +1 more source

Allergen Specificity in Specific IgE Cutoff [PDF]

JAMA Pediatrics, 2020
This cohort study examines the distribution of specific IgE levels to 5 common aeroallergens in 6-year-old Danish children.
Schoos, Ann Marie Malby, Hansen, Simone Møbius, Skov, Frederikke Rosenvinge, Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, Hans, Chawes, Bo Lund   +6 more
openaire   +3 more sources

Additional file 2 of Alternative approaches to identify core bacteria in Fucus distichus microbiome and assess their distribution and host-specificity

, 2022
Additional file 2. Supplementary Table 2 showing overlapping indicator ASVs of F. distichus on Calvert Island across sampling events and their overall specificity to determine core taxa. In step2, F.
Laura Wegener Parfrey (9905826), Jungsoo Park (5073371), Geneviève Lajoie (2930004), Katherine Davis (302610)   +3 more
core   +1 more source

Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania [PDF]

, 2012
Objective: To evaluate the diagnostic performance of two rapid detection tests (RDTs) for HIV 1/2 in plasma and in whole blood samples. Methods: More than 15,000 study subjects above the age of two years participated in two rounds of a cohort study to ...
Geldmacher Christof, Petra Clowes, Elmar Saathoff, Leonard Maboko, Wolfram Mwalongo, Clowes, Petra, Hoelscher, Michael, Kroidl, Arne L., Geldmacher, Christof, Michael Hoelscher, Arne L Kroidl, Kroidl Arne L., Hoelscher Michael, Harun Machibya, Kroidl, Inge, Machibya Harun, Machibya, Harun, Saathoff, Elmar, Inge Kroidl, Maganga, Lucas, Kroidl Inge, Maganga Lucas, Mwalongo Wolfram, Christof Geldmacher, Maboko Leonard, Mwalongo, Wolfram, Saathoff Elmar, Maboko, Leonard, Lucas Maganga, Clowes Petra   +29 more
core   +1 more source

Metabolic syndrome: Performance of five different diagnostic criterias

Indian Journal of Endocrinology and Metabolism, 2014
Background: The aim of this study is to describe the metabolic syndrome (MS) and to evaluate five diagnostic criteria of the MS with respect to their sensitivity and specificity in patients with type 2 diabetes mellitus (T2DM).
S Ogedengbe Onesi, U Ezeani Ignatius
doaj   +1 more source

A decade of progress in understanding LRRTM and Slitrk synaptic cell-adhesion molecules

Molecules and Cells
: For over a decade, synaptic cell-adhesion molecules (CAMs) have been recognized as fundamental determinants of neural circuit specificity and diversity.
Dongwook Kim, Byeongchan Kim, Ji Won Um, Jaewon Ko   +3 more
doaj   +1 more source

Comparison of Three Real-Time PCR Assays Targeting the SSU rRNA Gene, the COWP Gene and the DnaJ-Like Protein Gene for the Diagnosis of Cryptosporidium spp. in Stool Samples

Pathogens, 2021
As qualified microscopy of enteric parasitoses as defined by high diagnostic accuracy is difficult to maintain in non-endemic areas due to scarce opportunities for practicing with positive sample materials, molecular diagnostic options provide less ...
Felix Weinreich, Andreas Hahn, Kirsten Alexandra Eberhardt, Torsten Feldt, Fred Stephen Sarfo, Veronica Di Cristanziano, Hagen Frickmann, Ulrike Loderstädt   +7 more
doaj   +1 more source

An Optimized Enzyme-Nucleobase Pair Enables In Vivo RNA Metabolic Labeling with Improved Cell-Specificity

, 2022
Current transcriptome-wide analyses have identified a growing number of regulatory RNA with expression that is characterized in a cell-type-specific manner.
Christopher J. Halbrook (7872404), Scott X. Atwood (3605279), Samantha R. Levine (2047471), Chan Hong (14128960), Nan Dai (281544), Cecily Anaraki (14128963), Monika K. Singha (14128954), Jan Zimak (14128957), Mrityunjay Gupta (11409216), Robert C. Spitale (2350243)   +9 more
core   +1 more source

Transcriptomic analysis of wild Cannabis sativa: insights into tissue- and stage-specific expression and secondary metabolic regulation

BMC Genomics
Cannabis sativa is a medicinally and economically significant plant known for its production of cannabinoids, terpenoids, and other secondary metabolites.
Jinyuan Hu, Zishi Wang, He Xu, Zhenlong Wang, Ning Li, Rui Feng, Jianyu Yin, Fangru Liu, Baishi Wang   +8 more
doaj   +1 more source

Validation of the Use of Dried Blood Samples for the Detection of Toxoplasma gondii Antibodies in Stray Cats (Felis s. catus)

Pathogens, 2021
If validated beforehand, the analysis of dried blood on blotting paper (BP samples) is very useful for monitoring free-ranging animals. We aimed to validate this method for the detection of antibodies against Toxoplasma gondii in stray cats.
Julie Alice Simon, Dominique Aubert, Régine Geers, Isabelle Villena, Marie-Lazarine Poulle   +4 more
doaj   +1 more source