Results 51 to 60 of about 4,678,205 (343)

Sensitivity and Specificity of Rapid Diagnostic Test with Microscopic Gold Standard to Identify Plasmodium Species [PDF]

, 2016
Malaria is a main health problem in islands area which is under developed and isolated. Nation-wide, in 2014 Maluku province was recorded to have Annual Malaria Incident (AMI) value of 30.4%, positive incidents of 13.30%, ABER 3.76%, SPR 21.50%, and ...
Arwati, H. (Heny), Dachlan, Y. P. (Yoes), Keman, S. (Sudjajadi), Sillehu, S. (Sahrir)   +3 more
core  

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein, Melissa J. Rose, Scott Moerdler, Richard Ho   +3 more
wiley   +1 more source

Spatiotemporal dynamics of benzylisoquinoline alkaloid gene expression and co-expression networks during Papaver Somniferum developmental stages

Scientific Reports
Benzylisoquinoline alkaloids (BIAs) are essential secondary metabolites produced by Papaver somniferum, widely recognized for their pharmaceutical importance.
Zishi Wang, Quanzheng Yun, Jinyuan Hu, Zhen Wei, Deri Feng, Ning Li, He Xu, Lihong Fu, Zhenlong Wang, Shujin Li, Fangru Liu, Yan Wang, Bin Cong, Baishi Wang   +13 more
doaj   +1 more source

Accelerated corrosion behavior of DD32 alloy in the marine atmospheric environment

Journal of Materials Research and Technology
The corrosion of DD32 alloy in a marine atmospheric environment was investigated through accelerated corrosion tests. The corrosion morphology and products of alloy were discussed by the SEM, XRD, and XPS characterization.
Jianglong Ma, Guangming Kong, Zhiguo Liu, Lin Zhao, Ang Tian, Chuangwei Liu, Yiwei Wang   +6 more
doaj   +1 more source

Bottom-up and top-down influences at untrained conditions determine perceptual learning specificity and transfer

eLife, 2016
Perceptual learning is often orientation and location specific, which may indicate neuronal plasticity in early visual areas. However, learning specificity diminishes with additional exposure of the transfer orientation or location via irrelevant tasks ...
Ying-Zi Xiong, Jun-Yun Zhang, Cong Yu
doaj   +1 more source

Substrate specificity of amine oxidase [PDF]

, 1943
The tyramine oxidase activity of liver extracts found by Hare (1), the aliphatic amine oxidase activity of brain, kidney, and liver extracts observed by Pugh and Quastel (2), and the adrenalin oxidase activity of similar extracts noted by Blaschko ...
Alles, Gordon A., Heegaard, Erik V.
core  

A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen. [PDF]

, 2018
Anti-carbohydrate monoclonal antibodies (mAbs) hold great promise as cancer therapeutics and diagnostics. However, their specificity can be mixed, and detailed characterization is problematic, because antibody-glycan complexes are challenging to ...
Amon, Ron, Chen, Xi, Fleishman, Sarel J, Glushka, John N, Grant, Oliver C, Leviatan Ben-Arye, Shani, Makeneni, Spandana, Marshanski, Tal, Nivedha, Anita K, Norn, Christoffer, Padler-Karavani, Vered, Woods, Robert J, Yu, Hai   +12 more
core   +2 more sources

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1

Nature Communications
The ubiquitin system regulates eukaryotic physiology by modifying myriad substrate proteins. Substrate specificity and the assembly of ubiquitin signals are determined by ubiquitin ligases, some of which also modify non-protein biomolecules.
Barbara Orth, Pavel Pohl, Florian Aust, Yanlong Ji, Ayshwarya Seenivasan, Olexandr Dybkov, Xiaojun Julia Liang, Lars Bock, Florian Leidner, Sophie Levantovsky, Patrick Schardey, Pascal Sander, Nathanael J. Disch, Masanja L. Trautz, Athanasia Mizi, Argyris Papantonis, Christof Lenz, Helmut Grubmüller, Wieland Steinchen, Christian Behrends, Henning Urlaub, Matthias Gehringer, Sonja Lorenz   +22 more
doaj   +1 more source

The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions

Cell Reports
Summary: Neuroinflammation is a well-established risk factor for various neurological disorders and cognitive decline. However, the precise molecular mechanisms linking inflammation with neuropsychiatric symptoms remain unclear.
Hyeji Jung, Byeongchan Kim, Gyubin Jang, Hyeonho Kim, Ae-Ree Lee, Sung-Hyun Yoon, Kyung-Seo Lee, Gaeun Hyun, Younghye Kim, Jaewon Ko, Je-Wook Yu, Ji Won Um   +11 more
doaj   +1 more source