Results 71 to 80 of about 2,010,640 (293)

A Numerical Procedure for Proving Specific Strict One-Variable Inequalities in Specific Finite Intervals [PDF]

open access: yesarXiv, 2017
A numerical procedure and its MAPLE implementation capable of rigorously, albeit in a brute-force manner, proving specific strict one-variable inequalities in specific finite intervals is described. The procedure is useful, for instance, to affirm strict lower bounds of specific functions.
arxiv  

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Synchronic variation and diachronic change in the expression of indefinite reference: evidence from historical German

open access: yesZeitschrift für Sprachwissenschaft, 2015
The present article discusses the semantic and discourse-pragmatic properties of different competing types of indefinite noun phrases in Old High German, the earliest attested period of German. In particular, it investigates the behavior of indefinites
Petrova Svetlana
doaj   +1 more source

Systems with Almost Specification Property May Have Zero Entropy [PDF]

open access: yesarXiv, 2015
It is shown that there exist systems having almost specification property and zero entropy. Since Sigmund has shown that systems with specification property must have positive entropy, this result reveals further the difference between almost specification and specification.
arxiv  

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Gradient Effects of Animacy on Differential Object Marking in Turkish

open access: yesOpen Linguistics, 2019
Animacy is a pervasive cognitive category that is displayed in the grammatical behavior of the world’s languages through categorical or gradient effects.
Krause Elif, von Heusinger Klaus
doaj   +1 more source

An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases

open access: yeseLife, 2014
Malate and lactate dehydrogenases (MDH and LDH) are homologous, core metabolic enzymes that share a fold and catalytic mechanism yet possess strict specificity for their substrates.
Jeffrey I Boucher   +4 more
doaj   +1 more source

One-sided almost specification and intrinsic ergodicity [PDF]

open access: yesarXiv, 2016
Shift spaces with the specification property are intrinsically ergodic, i.e. they have a unique measure of maximal entropy. This can fail for shifts with the weaker almost specification property. We define a new property called one-sided almost specification, which lies in between specification and almost specification, and prove that it guarantees ...
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Bottom-up and top-down influences at untrained conditions determine perceptual learning specificity and transfer

open access: yeseLife, 2016
Perceptual learning is often orientation and location specific, which may indicate neuronal plasticity in early visual areas. However, learning specificity diminishes with additional exposure of the transfer orientation or location via irrelevant tasks ...
Ying-Zi Xiong, Jun-Yun Zhang, Cong Yu
doaj   +1 more source

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