Results 81 to 90 of about 4,525,804 (339)

Neuropsychological Diagnostic Accuracy: Factors That Might Lead to a Wrong Diagnosis and How to Avoid Them

open access: yesRevista Iberoamericana de Psicología, 2019
False positives and false negatives in neuropsychological assessment can occur due to different reasons and they could have serious consequences such as the administration of an unnecessary treatment that may cause adverse effects and failure to provide ...
Jeniffer Ortega Marin, Dra.
doaj   +1 more source

Variation in Specificity of HIV Rapid Diagnostic Tests over Place and Time: An Analysis of Discordancy Data Using a Bayesian Approach [PDF]

open access: yes, 2015
BACKGROUND Recent trends to earlier access to anti-retroviral treatment underline the importance of accurate HIV diagnosis. The WHO HIV testing strategy recommends the use of two or three rapid diagnostic tests (RDTs) combined in an algorithm and assume ...
Glass, Kathryn   +5 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Simultaneous determination of the lipoxygenase and hydroperxide lyase specificity in olive fruit pulp

open access: yesGrasas y Aceites, 2000
Olive pulp lipoxygenase regiospecificity and hydroperoxide lyase substrate specificity are important parameters in order to justify the volatile composition of olive oil. A new radiolabelling method to determine simultaneously these properties using only
Joaquín J. Salas
doaj   +1 more source

Topicality and (Non-)Specificity in Mandarin [PDF]

open access: yes, 2001
Current analyses of specificity are unable to provide an explanatory account for why specific and nonspecific uses of indefinites are available. While Abusch (1994), Reinhart (1997), and Kratzer (1998) provide successful mechanisms for deriving specific ...
Portner, Paul
core  

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

SPECIFICS. [PDF]

open access: yesThe Lancet
n ...
openaire   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

The evolution of complex gene regulation by low specificity binding sites

open access: yes, 2012
Transcription factor binding sites vary in their specificity, both within and between species. Binding specificity has a strong impact on the evolution of gene expression, because it determines how easily regulatory interactions are gained and lost ...
Plotkin, Joshua B.   +1 more
core   +1 more source

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