Results 41 to 50 of about 198,283 (303)

Studies on Pitting Corrosion of Al-Cu-Li Alloys Part II: Breakdown Potential and Pit Initiation. [PDF]

, 2019
Prediction of the accumulated pitting corrosion damage in aluminum-lithium (Al-Li) is of great importance due to the wide application of these alloys in the aerospace industry.
Ghanbari, Elmira, Lei, Xiaowei, Macdonald, Digby D, Saatchi, Alireza   +3 more
core   +2 more sources

Graphene in cryo-EM specimen optimization

Current Opinion in Structural Biology
Specimen preparation is a critical but challenging step in high-resolution cryogenic electron microscopy (cryo-EM) structural analysis of macromolecules. In the past decade, graphene has gained much recognition as the supporting substrate to optimize cryo-EM specimen preparation.
Nan Liu, Hong-Wei Wang
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens

Journal of Proteome Research, 2023
The foundation for integrating mass spectrometry (MS)-based proteomics into systems medicine is the development of standardized start-to-finish and fit-for-purpose workflows for clinical specimens. An essential step in this pursuit is to highlight the common ground in a diverse landscape of different sample preparation techniques and liquid ...
Oliver Kardell, Christine von Toerne, Juliane Merl-Pham, Ann-Christine König, Marcel Blindert, Teresa K. Barth, Julia Mergner, Christina Ludwig, Johanna Tüshaus, Stephan Eckert, Stephan A. Müller, Stephan Breimann, Pieter Giesbertz, Alexander M. Bernhardt, Lisa Schweizer, Vincent Albrecht, Daniel Teupser, Axel Imhof, Bernhard Kuster, Stefan F. Lichtenthaler, Matthias Mann, Jürgen Cox, Stefanie M. Hauck   +22 more
openaire   +5 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Creep behavior analysis of conical observation window for human occupied vehicle based on ABAQUS

Zhongguo Jianchuan Yanjiu, 2022
ObjectivesThe observation window is the most important component of a human occupied vehicle (HOV) for personnel and structural safety. As such, it is extremely important to accurately calculate its creep performance under long-period loads. MethodsFirst,
Qinghai DU, Haigang JIANG, Xiaokang HU
doaj   +1 more source

Material plastic properties characterization using a generic algorithm and finite element method modelling of the plane-strain small punch test [PDF]

, 2010
In this paper, a novel plane strain small punch test (SPT) method is proposed for material plastic properties characterization. The plane strain SPT is different from the standard SPT in the two ways: (a) a long thin rectangular specimen (with dimensions
Boyle, Jim, Dun, Craig, Hakoda, Kenji, Ismail, Mohd., Pan, Wenke, Ramlan, Mohd.   +5 more
core   +1 more source

Alignment of cryo-EM movies of individual particles by optimization of image translations

, 2015
Direct detector device (DDD) cameras have revolutionized single particle electron cryomicroscopy (cryo-EM). In addition to an improved camera detective quantum efficiency, acquisition of DDD movies allows for correction of movement of the specimen, due ...
Brubaker, Marcus A., Rubinstein, John L.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Innovative vibration technique applied to polyurethane foam as a viable substitute for conventional fatigue testing

Journal of the Mechanical Behavior of Materials, 2012
Lifetime prediction using three-point bending (TPB) can at times be prohibitively time consuming and costly, whereas vibration testing at higher frequency may potentially save time and revenue. A vibration technique that obtains lifetimes that reasonably
Peralta Alexander, Just-Agosto Frederick, Shafiq Basir, Serrano David   +3 more
doaj   +1 more source