Results 41 to 50 of about 103,020 (264)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Parametric shape optimization of biaxial tensile specimen [PDF]
PAMM, 2016 AbstractCommon cruciform specimen for biaxial tensile testing of sheet moulding compound, take damage and finally fail in uniaxially loaded areas. When using these specimen, an observation of damage initialization and failure in biaxially loaded areas is, therefore, not possible.
Bauer, J. +4 more
openaire +2 more sources
Hybridizing a matheuristic with ALNS for the optimal collection and delivery of medical specimens
International Transactions in Operational Research, 2023 AbstractThe past few years of the COVID‐19 pandemic outbreak have shown that optimal management of medical specimens is a key aspect of healthcare logistics, both for addressing the delivery of perishable items such as vaccines, and for ensuring the timely analysis of swabs and samples.
Daniele Ferone +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Scientific ReportsPullout tests are usually used to test the anchoring capacity of rockbolts and to study their anchoring mechanisms. In this study, the influence of the diameter of the concrete matrix specimen to the ultimate pull force of the bolt was investigated ...
Minglu Xing +8 more
doaj +1 more source
Creep behavior analysis of conical observation window for human occupied vehicle based on ABAQUS
Zhongguo Jianchuan Yanjiu, 2022 ObjectivesThe observation window is the most important component of a human occupied vehicle (HOV) for personnel and structural safety. As such, it is extremely important to accurately calculate its creep performance under long-period loads. MethodsFirst,
Qinghai DU, Haigang JIANG, Xiaokang HU
doaj +1 more source
Progress towards an optimal specimen support for electron cryomicroscopy
Current Opinion in Structural Biology, 2016 The physical principles of electron-specimen interaction govern the design of specimen supports for electron cryomicroscopy (cryo-EM). Supports are constructed to suspend biological samples within the vacuum of the electron microscope in a way that maximises image contrast.
Russo, Christopher J, Passmore, Lori A
openaire +3 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Composites Part C: Open AccessGlass fiber-reinforced polymer composites are important structural materials and are widely used in structure engineering. In this study, a new V-notch non-standard tensile specimen is proposed.
Hao Jiang +10 more
doaj +1 more source