Results 61 to 70 of about 198,283 (303)

Optimal z-axis scanning parameters for gynecologic cytology specimens

Journal of Pathology Informatics, 2013
The use of virtual microscopy (VM) in clinical cytology has been limited due to the inability to focus through three dimensional (3D) cell clusters with a single focal plane (2D images). Limited information exists regarding the optimal scanning parameters for 3D scanning.The purpose of this study was to determine the optimal number of the focal plane ...
Amber D Donnelly, Maheswari S Mukherjee, Elizabeth R Lyden, Julia A Bridge, Subodh M Lele, Najia Wright, Mary F McGaughey, Alicia M Culberson, Adam J Horn, Whitney R Wedel, Stanley J Radio   +10 more
openaire   +3 more sources

Nanoscale imaging of clinical specimens using pathology-optimized expansion microscopy [PDF]

Nature Biotechnology, 2017
Expansion microscopy (ExM), a method for improving the resolution of light microscopy by physically expanding a specimen, has not been applied to clinical tissue samples. Here we report a clinically optimized form of ExM that supports nanoscale imaging of human tissue specimens that have been fixed with formalin, embedded in paraffin, stained with ...
Zhao, Yongxin, Bucur, Octavian, Irshad, Humayun, Chen, Fei, Weins, Astrid, Stancu, Andreea L, Oh, Eun-Young, DiStasio, Marcello, Torous, Vanda, Glass, Benjamin, Stillman, Isaac E, Schnitt, Stuart J, Beck, Andrew H, Boyden, Edward S   +13 more
openaire   +4 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

TIPS FOR A SUCCESSFUL LOGO [PDF]

, 2011
In the hydraulic bulge test, flow curves are determined by applying a hydrostatic pressure to one side of a clamped sheet metal specimen, which bulges freely into a circular cavity under the pressure.
Chystykova, K, Shynkarenko, N
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Measurement Procedures for the Electrical Characterization of Oxide Thin Films [PDF]

, 2009
This paper describes a measurement system for the electrical characterization of oxide thin films. Such films can be produced using plasma-sputtering processes and permit the realization of a large set of high-performance components, such as capacitors ...
Carullo, Alessio, Grassini, Sabrina, Parvis, Marco   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Study on the optimal design of specimens for stiffness coefficients identification of glass fiber-reinforced polymer composites by virtual fields method

Composites Part C: Open Access
Glass fiber-reinforced polymer composites are important structural materials and are widely used in structure engineering. In this study, a new V-notch non-standard tensile specimen is proposed.
Hao Jiang, Rongxin Zhu, Yan Liu, Zongzhe Man, Zhiyuan Yang, Yingkai Wu, Xiaowei Li, Yu Jiang, Qifeng Xiao, Zhenkun Lei, Ruixiang Bai   +10 more
doaj   +1 more source

Determination of Radiative Heat Transfer Coefficient at High Temperatures Using a Combined Experimental-Computational Technique

Measurement Science Review, 2015
The radiative heat transfer coefficient at high temperatures is determined using a combination of experimental measurement and computational modeling.
Kočí Václav, Kočí Jan, Korecký Tomáš, Maděra Jiří, Černý Robert Č   +4 more
doaj   +1 more source

Mechanical Properties of Friction Stir Welded AA1050-H14 and AA5083-H111 Joint: Sampling Aspect

Metals, 2020
Welding of dissimilar aluminium alloys has been a challenge for a long period until the discovery of the solid-state welding technique called friction stir welding (FSW).
Velaphi Msomi, Nontle Mbana
doaj   +1 more source