Results 61 to 70 of about 3,158 (251)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Study on the optimal design of specimens for stiffness coefficients identification of glass fiber-reinforced polymer composites by virtual fields method

Composites Part C: Open Access
Glass fiber-reinforced polymer composites are important structural materials and are widely used in structure engineering. In this study, a new V-notch non-standard tensile specimen is proposed.
Hao Jiang, Rongxin Zhu, Yan Liu, Zongzhe Man, Zhiyuan Yang, Yingkai Wu, Xiaowei Li, Yu Jiang, Qifeng Xiao, Zhenkun Lei, Ruixiang Bai   +10 more
doaj   +1 more source

Design optimization of cruciform specimens for biaxial fatigue loading [PDF]

Fracture and Structural Integrity, 2014
In order to correctly assess the biaxial fatigue material properties one must experimentally test different load conditions and stress levels. With the rise of new in-plane biaxial fatigue testing machines, using smaller and more efficient electrical ...
R. Baptista , R. A. Claudio , L. Reis , I. Guelho , M. Freitas , J. F. A. Madeira   +5 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Determination of Radiative Heat Transfer Coefficient at High Temperatures Using a Combined Experimental-Computational Technique

Measurement Science Review, 2015
The radiative heat transfer coefficient at high temperatures is determined using a combination of experimental measurement and computational modeling.
Kočí Václav, Kočí Jan, Korecký Tomáš, Maděra Jiří, Černý Robert Č   +4 more
doaj   +1 more source

Comparison and optimization for DNA extraction of archived fish specimens

MethodsX, 2019
The DNA extracted from museum alcohol-fixed specimens can be a valuable source of information for solving taxonomic, phylogenetic, ecological and conservational questions. However, this type of DNA, also called ancient DNA, is routinely obtained in small portions and highly fragmented.
Priscilla C. Silva, Maria Claudia Malabarba, Richard Vari (In memoriam), Luiz R. Malabarba   +3 more
openaire   +3 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Fatigue strength characterization of Al-Si cast material incorporating statistical size effect

MATEC Web of Conferences, 2018
Cast aluminium components may exhibit material imperfections such as shrinkage and gas pores, or oxide inclusions. Therefore, the fatigue resistance is significantly influenced by the size and location of these inhomogenities. In this work, two different
Aigner Roman, Leitner Martin, Stoschka Michael   +2 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Enhancing preanalytic surgical specimen management: experience of a system implementation initiative

Diagnostic Pathology
Background /Objectives Preanalytic quality control of surgical specimens is often inadequately managed. This study aimed to share the experience of improving quality through the implementation of a system for preanalytic surgical specimens. Methods After
Peirong Chen, Weiming Qiu
doaj   +1 more source