Results 111 to 120 of about 67,751 (242)
Movement Disorders, EarlyView.Abstract Background Peripheral immune dysregulation has been implicated in Parkinson's disease (PD) progression, but whether motor deterioration reflects accelerated nigrostriatal degeneration or residual dopaminergic reserve remains unclear. Objectives To examine whether baseline and time‐varying neutrophil‐to‐lymphocyte ratio (NLR) relate to motor ...
Osman Kahveci, Ulaş Ay, Tamer Demiralp
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Parkinson's disease (PD) is frequently accompanied by neuropsychiatric symptoms (NPS), including cognitive impairment, which often emerge early and co‐occur. Their long‐term evolution remains incompletely characterized, particularly in biomarker‐positive cohorts.
Izabelle Schoen +10 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background The cerebellum is increasingly recognized as a key contributor to cognitive reserve and network organization in Parkinson's disease (PD). However, the relationship of cerebello‐cortical and cerebello‐basal ganglia connectivity with cognitive status and nigrostriatal integrity remains incompletely understood.
Chi‐Ying R. Lin +6 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract The neuropathology of Parkinson's disease (PD) is characterized in part by the degeneration of catecholaminergic neurons, particularly dopaminergic neurons in the substantia nigra pars compacta (SNpc) and noradrenergic neurons in the locus coeruleus (LC), yet no validated in vivo biomarker quantifies this process.
Rayo Akande +5 more
wiley +1 more source
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To introduce a robust approach for non‐contrast‐enhanced free‐breathing functional lung MRI based on independent component analysis (ICA), addressing key limitations of standard methods such as sensitivity to irregular breathing or irregular heartbeat.
Laura Rozo Pardo +8 more
wiley +1 more source
Precision Radiation Oncology, EarlyView.Scheme 1. Schematic illustration of the synthesis and therapeutic evaluation of PLA‐g‐PAO microspheres (PLA‐g‐PAO‐Ms). Monodisperse PLA microspheres (PLA‐Ms) were initially fabricated via microfluidic technology. Surface grafting of acrylonitrile monomers was subsequently achieved through radiation‐induced graft polymerization, followed by ...
Xingliang Liu +7 more
wiley +1 more source
Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation
Respirology, EarlyView.ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley +1 more source
Levodopa‐Responsive Parkinsonism Preceded by Isolated Upper Limb Tremor Associated with PTEN Variant
Movement Disorders Clinical Practice, EarlyView.
Sacha E. Gandhi +3 more
wiley +1 more source