Results 121 to 130 of about 67,751 (242)

Spectral Submanifolds of Delay Systems: Control in Continuous and Discrete Time

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT This paper presents both continuous‐time and discretization‐based approaches for constructing spectral submanifolds (SSMs) for time delay systems. The continuous‐time approach built upon sun–star calculus, reformulates the governing delay differential equation (DDE) as an operator differential equation (OpDE).
Bence Szaksz   +2 more
wiley   +1 more source

Advances in research on layered double hydroxides for biomedical applications

open access: yesSmart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang   +13 more
wiley   +1 more source

Response to the Correspondence Regarding “Cutaneous Metastasis From Papillary Thyroid Carcinoma Eight Years After Initial Surgery”

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT We sincerely thank Dr. Sengul and colleagues for their insightful comments on our case report of skin metastasis in papillary thyroid cancer (PTC). They questioned the adequacy of local excision and suggested completion thyroidectomy to enable radioactive iodine (RAI) therapy or systemic therapy. We appreciate their perspective but explain our
Yi‐Qing Gao   +3 more
wiley   +1 more source

Quantitative Dual‐Energy CT Perfusion Versus SPECT/CT V/Q Scintigraphy for Preoperative Lung Function Assessment: A Prospective Cohort Study

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Accurate preoperative physiological assessment is critical for high‐risk patients undergoing lung resection to predict postoperative lung function. This study compared quantitative dual‐energy CT (DECT) perfusion with SPECT/CT for lobar perfusion mapping in an at‐risk oncological cohort.
Jack Edward Liu   +6 more
wiley   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

open access: yesBritish Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka   +3 more
wiley   +1 more source

A DPP6‐Targeted PET Tracer for Non‐Invasive Imaging of Transplanted Human Islets

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Dipeptidyl peptidase‐like protein 6 (DPP6) is a potential molecular imaging biomarker for pancreatic and transplanted islets of Langerhans. 4hD29 is a single‐domain antibody with nanomolar affinity for DPP6. Here, we demonstrate the generation and validation of [68Ga]Ga‐NOTA‐4hD29 for Positron Emission Tomography (PET) imaging of ...
Amina Khalil   +11 more
wiley   +1 more source

The Role of Reprojected Planar Data Derived from Fast Whole-Body Bone SPECT/CT. [PDF]

open access: yesDiagnostics (Basel)
Alqahtani MM   +7 more
europepmc   +1 more source

Research Review: A scoping review exploring the needs, barriers, and facilitators to the collection of biological data in adolescence for mental health research

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background There is increasing recognition of the challenge of representativeness in data, including economic, social, and ethnic diversity, in biological mental health research. This is a particular challenge in adolescence, where brain and body development are impacted by the environment.
Courtney Worrell   +29 more
wiley   +1 more source

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