Results 21 to 30 of about 95,958 (315)

Preclinical validations of [18F]FPyPEGCBT-c(RGDfK): a 18F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis

open access: yesEJNMMI Radiopharmacy and Chemistry, 2016
Background αVβ3, αVβ5 and α5β1 integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to healthy tissues; thereby they have been selected as promising therapeutic targets. Positron emission tomography
Didier J. Colin   +3 more
doaj   +1 more source

Redox-sensitive iodinated polymersomes carrying histone deacetylase inhibitor as a dual-functional nano-radiosensitizer for enhanced radiotherapy of breast cancer

open access: yesDrug Delivery, 2021
Radiotherapy (RT) is a frequently used means in clinical tumor treatment. The outcome of RT varies, however, to a great extent, due to RT resistance or intolerable dose, which might be resolved by the development of radio-sensitizing strategies. Here, we
Zhehong Zhu   +9 more
doaj   +1 more source

Adaptive SPECT [PDF]

open access: yesIEEE Transactions on Medical Imaging, 2008
Adaptive imaging systems alter their data-acquisition configuration or protocol in response to the image information received. An adaptive pinhole single-photon emission computed tomography (SPECT) system might acquire an initial scout image to obtain preliminary information about the radiotracer distribution and then adjust the configuration or sizes ...
Harrison H, Barrett   +6 more
openaire   +2 more sources

Distinct cerebral cortical perfusion patterns in idiopathic normal‐pressure hydrocephalus

open access: yesHuman Brain Mapping, Volume 44, Issue 1, Page 269-279, January 2023., 2023
The present study investigates cerebral blood flow (CBF) and cortical thickness using surface‐based analysis of early‐phase 18F‐florbetaben PET and MRI in patients with idiopathic normal‐pressure hydrocephalus (INPH). INPH patients had significantly increased CBF with a concomitant increase in cortical thickness in areas located in the high convexity ...
Kyunghun Kang   +10 more
wiley   +1 more source

EFECTO DE LOS PARÁMETROS DE ADQUISICIÓN EN IMÁGENES SPECTCEREBRALES: UN ESTUDIO SIMIND MONTECARLO

open access: yesAnales (Asociación Física Argentina), 2023
In this work cerebral SPECT images were simulated using the SIMIND Monte Carlo code. The specific purpose was the detection of characteristic Alzheimer’s disease (EA) and Major Depression (DM) lesions in simulated brain images, modeling the data ...
J. Sanchez, C. Y. Chain, L. H. Illanes
doaj   +1 more source

SPECT/CT [PDF]

open access: yesJournal of Nuclear Medicine, 2008
In view of the commercial success of integrated PET/CT scanners, there is an increasing interest in comparable SPECT/CT systems. SPECT in combination with CT enables a direct correlation of anatomic information and functional information, resulting in better localization and definition of scintigraphic findings.
Andreas K, Buck   +10 more
openaire   +2 more sources

Cross-domain Iterative Network for Simultaneous Denoising, Limited-angle Reconstruction, and Attenuation Correction of Low-dose Cardiac SPECT [PDF]

open access: yesarXiv, 2023
Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of ischemic heart diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-angle (LA) SPECT enables faster scanning and reduced hardware costs but results in lower reconstruction accuracy.
arxiv  

PET and SPECT in NeurologyPET and SPECT in PsychiatryPET and SPECT of Neurobiological Systems [PDF]

open access: yesJournal of Nuclear Medicine, 2015
R.A.J.O. Diercks, A. Otte, E.F.J. de Vries, and A. van Waarde, eds. New York, NY: Springer, 2014, 818–1,112 pages, $399 each There is a series of 3 new books on PET and SPECT that is marvelous in terms of editorial coordination and comprehensiveness of content.
openaire   +2 more sources

Determination of the Energy Windows for the Triple Energy Window Scatter Correction Method in Gadolinium-159 Single Photon Emission Computed Tomography Using Monte Carlo Simulation [PDF]

open access: yesIranian Journal of Medical Physics, 2019
Introduction: In radionuclide imaging, object scatter is one of the major factors leading to image quality degradation. Therefore, the correction of scattered photons might have a great impact on improving the image quality.
Youssef Bouzekraoui   +3 more
doaj   +1 more source

Partial volume effect in SPECT & PET imaging and impact on radionuclide dosimetry estimates [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2023
Objective(s): The spatial resolution of emission tomographic imaging systems can lead to a significant underestimation in the apparent radioactivity concentration in objects of size comparable to the resolution volume of the system. The aim of this study
Harry Marquis   +2 more
doaj   +1 more source

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