Results 41 to 50 of about 67,751 (242)

A Comparative Study of Regional Cerebral Blood Flow Asymmetry Index in Stroke Patients with or without Poststroke Depression Using 99mTc-ECD Single-Photon Emission Computed Tomography

open access: yesWorld Journal of Nuclear Medicine, 2022
Introduction Stroke is a major cause of death and disability around the globe. The development of depression following a stroke further increases the disability and impairs functional recovery. In recent decades, despite the advancement in structural and
Pradeep Kumar Maurya   +5 more
doaj   +1 more source

PET and SPECT in NeurologyPET and SPECT in PsychiatryPET and SPECT of Neurobiological Systems [PDF]

open access: yesJournal of Nuclear Medicine, 2015
R.A.J.O. Diercks, A. Otte, E.F.J. de Vries, and A. van Waarde, eds. New York, NY: Springer, 2014, 818–1,112 pages, $399 each There is a series of 3 new books on PET and SPECT that is marvelous in terms of editorial coordination and comprehensiveness of content.
openaire   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Possibilities of Hybrid SPECT/CT with 123I-MIBG for Visualizing the Ganglia of the Cardiac Autonomic Nervous System in Healthy Volunteers

open access: yesВестник рентгенологии и радиологии, 2020
Objective – to study the characteristics of the distribution and visualization of ganglionated plexuses in the left atrium (LAGP) in healthy volunteers.Objective and methods. The investigation enrolled 15 healthy volunteers (median age 31 [26; 41] years).
N. A. Nikitin   +4 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Preparation and Biological Evaluation of [111In]-THPP [5, 10, 15, 20-tetrakis (4-Hydroxyphenyl) Porphyrin] Complex in Healthy Rats Via SPECT Imaging [PDF]

open access: yesمجله علوم و فنون هسته‌ای, 2016
The aim of this research was the synthesis of 111In-THPP, and its evaluation as a new imaging agent. The 111In-THPP radiotracer was synthesized by 111InCl3 and 5, 10, 15, 20-tetrakis (4-hydroxyphenyl) porphyrin) (THPP) in solution for 60 min at 80˚C.
A.R Jalilian   +3 more
doaj  

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Facile Synthesis of a Bis‐α‐aryl‐Substituted Pyclen‐Based Heptadentate Lanthanide Chelator for Ultra‐Robust and High‐Contrast MRI Agents and for Radiopharmaceuticals

open access: yesAngewandte Chemie, EarlyView.
A facile synthesis involving a three‐component Petasis reaction is reported to construct bis‐α‐aryl‐substituted PCTAs. The synthesis is the simplest among all previously reported work on α‐substituted PCTAs. One of the isomers results in a Gd complex that showed significantly improved robustness despite being heptadentate and q = 2. This complex should
Pak‐Lun Lam   +15 more
wiley   +2 more sources

Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea   +53 more
wiley   +1 more source

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