Results 121 to 130 of about 24,551,019 (389)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

OSSE spectral analysis techniques [PDF]

Analysis of the spectra from the Oriented Scintillation Spectrometer Experiment (OSSE) is complicated because of the typically low signal to noise (approx. 0.1 percent) and the large background variability.
Brown, K. M., Grabelsky, D. A., Johnson, W. N., Jung, G. V., Kinzer, R. L., Kroeger, R. A., Kurfess, J. D., Matz, S. M., Purcell, W. R., Strickman, M. S.   +9 more
core   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Stability of an additive-quadratic functional equation in modular spaces

Open Mathematics
Using the direct method, we prove the Hyers-Ulam-Rassias stability of the following functional equation: ϕ(x+y,z+w)+ϕ(x−y,z−w)−2ϕ(x,z)−2ϕ(x,w)=0\phi \left(x+y,z+w)+\phi \left(x-y,z-w)-2\phi \left(x,z)-2\phi \left(x,w)=0 in ρ\rho -complete convex modular ...
Baza Abderrahman, Rossafi Mohamed, Park Choonkil, Donganont Mana   +3 more
doaj   +1 more source

Synthesis and complete NMR spectral assignments of new benzylamino coumarin derivative [PDF]

Bulletin of Natural Sciences Research, 2020
This research involves the reaction of 4-chloro-3-nitrocoumarin and (4-methoxyphenyl)methanamine, whereby a novel coumarin derivative 4-[(4-methoxybenzyl) amino]-3-nitro-2H-chromen-2-one was obtained in good yield.
Dekić Vidoslav, Radulović Niko, Ristić Milenko, Dekić Biljana, Ristić Novica   +4 more
doaj  

Spectral analysis of stationary random bivariate signals

, 2017
A novel approach towards the spectral analysis of stationary random bivariate signals is proposed. Using the Quaternion Fourier Transform, we introduce a quaternion-valued spectral representation of random bivariate signals seen as complex-valued ...
Bihan, Nicolas Le, Chainais, Pierre, Flamant, Julien   +2 more
core   +2 more sources

pavo 2.0: new tools for the spectral and spatial analysis of colour in R

bioRxiv, 2018
Biological colouration presents a canvas for the study of ecological and evolutionary processes. Enduring interest in colour-based phenotypes has driven, and been driven by, improved techniques for quantifying colour patterns in ever-more relevant ways ...
Rafael Maia, H. Gruson, J. Endler, T. White   +3 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Visible spectroscopy of the new ESO Large Program on trans-Neptunian objects and Centaurs: final results

, 2009
A second large programme (LP) for the physical studies of TNOs and Centaurs, started at ESO Cerro Paranal on October 2006 to obtain high-quality data, has recently been concluded.
A. Alvarez-Candal, A. Delsanti, A. Doressoundiram, A. Guilbert, Alvarez-Candal, Barucci, Barucci, Barucci, Binzel, Boehnhardt, Brown, C. de Bergh, D. Perna, de Bergh, Dotto, E. Dotto, F. DeMeo, F. Merlin, Fitzsimmons, Fornasier, Fornasier, Fornasier, Fornasier, Guilbert, Jewitt, Lacerda, Lacerda, Lacerda, Lazzarin, Licandro, Licandro, Luu, Luu, M. A. Barucci, Marchi, Morbidelli, Ortiz, Peixinho, Peixinho, Pinilla-Alonso, Pinilla-Alonso, Pinilla-Alonso, Ragozzine, S. Fornasier, Santos-Sanz, Spearman, Tegler, Tegler, Trujillo, Vilas   +49 more
core   +3 more sources

A Note on Summability Methods and Spectral Analysis [PDF]

, 1957
Carl Herz
openalex   +1 more source