Results 51 to 60 of about 234,781 (273)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Spectral clustering for jet physics
Journal of High Energy Physics, 2022 We present a new approach to jet definition alternative to clustering methods, such as the anti-kT scheme, that exploit kinematic data directly. Instead the new method uses kinematic information to represent the particles in a multidimensional space, as ...
Giorgio Cerro +5 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Applications in Plant Sciences, 2020 Premise Statistical methods used by most morphologists to validate species boundaries (such as principal component analysis [PCA] and non‐metric multidimensional scaling [nMDS]) are limiting because these methods are mostly used as visualization methods,
Preeti Saryan +2 more
doaj +1 more source
A Short Text Clustering Algorithm Based on Spectral Cut [PDF]
Jisuanji gongcheng, 2016 Short text has the characteristics of sparsity and high dimension,and the existing clustering algorithm for the large-scale short text has low accuracy and efficiency.Aiming at this problem,a novel clustering method based on spectral clustering theory ...
LI Xiaohong,XIE Meng,MA Huifang,HE Tingnian
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Remote Sensing, 2016 Remote sensing image clustering is a challenging task considering its intrinsic complexity. Recently, by combining the spectral and spatial information of the remote sensing data, the clustering performance can be dramatically enhanced, termed as ...
Ailong Ma, Yanfei Zhong, Liangpei Zhang
doaj +1 more source
Kernel Spectral Curvature Clustering (KSCC)
, 2009 Multi-manifold modeling is increasingly used in segmentation and data representation tasks in computer vision and related fields. While the general problem, modeling data by mixtures of manifolds, is very challenging, several approaches exist for ...
Atev, S., Chen, G., Lerman, G.
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source