Results 71 to 80 of about 1,461,923 (295)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Remote Sensing, 2016 Remote sensing image clustering is a challenging task considering its intrinsic complexity. Recently, by combining the spectral and spatial information of the remote sensing data, the clustering performance can be dramatically enhanced, termed as ...
Ailong Ma, Yanfei Zhong, Liangpei Zhang
doaj +1 more source
A Short Text Clustering Algorithm Based on Spectral Cut [PDF]
Jisuanji gongcheng, 2016 Short text has the characteristics of sparsity and high dimension,and the existing clustering algorithm for the large-scale short text has low accuracy and efficiency.Aiming at this problem,a novel clustering method based on spectral clustering theory ...
LI Xiaohong,XIE Meng,MA Huifang,HE Tingnian
doaj +1 more source
Hierarchical kernel spectral clustering [PDF]
Neural Networks, 2012 Kernel spectral clustering fits in a constrained optimization framework where the primal problem is expressed in terms of high-dimensional feature maps and the dual problem is expressed in terms of kernel evaluations. An eigenvalue problem is solved at the training stage and projections onto the eigenvectors constitute the clustering model.
Alzate Perez, Carlos, Suykens, Johan
openaire +4 more sources
Multi-type relational clustering approaches : current state-of-the-art and new directions [PDF]
, 2008 The proliferation of multi-type relational datasets in a number of important real-world applications and the limitations resulting from the transformation of such datasets to fit propositional data mining approaches have led to the emergence of the ...
Anand, Sarabjot Singh, Li, Tao
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Fast kernel spectral clustering [PDF]
Neurocomputing, 2017 Abstract Spectral clustering suffers from a scalability problem in both memory usage and computational time when the number of data instances N is large. To solve this issue, we present a fast spectral clustering algorithm able to effectively handle millions of datapoints at a desktop PC scale.
Langone, Rocco, Suykens, Johan
openaire +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source