Results 41 to 50 of about 69,048 (297)

Construction and evaluation of a risk prediction model for preoperative lymph node metastasis in non-small cell lung cancer using spectral CT and multiple factors

open access: yes徐州医科大学学报
Objective To investigate the value of a risk prediction model constructed by spectral CT and multiple factors for preoperative lymph node metastasis (LNM) in non-small cell lung cancer (NSCLC).Methods Retrospective analysis was conducted on 150 patients ...
WANG Xiaoyi   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Spectral CT images of hamartoma.

open access: yes, 2016
Spectral CT images of a 50-year-old woman with hamartoma in AP (A-D) and VP (E-H): 70 keV images after enhancement (A, E), Water-based images (B, F), Iodine-based images (C, G) and spectral curves (D, H). The spectral HU curves were respectively arterial
Mingji Yu (2163295)   +7 more
core   +1 more source

Molecular Imaging of Pulmonary Tuberculosis in an Ex-Vivo Mouse Model Using Spectral Photon-Counting Computed Tomography and Micro-CT

open access: yesIEEE Access, 2021
Assessment of disease burden and drug efficacy is achieved preclinically using high resolution micro computed tomography (CT). However, micro-CT is not applicable to clinical human imaging due to operating at high dose.
Chiara Lowe   +56 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Spectral CT images of adenocarcinoma.

open access: yes, 2016
Spectral CT images of a 46-year-old man with adenocarcinoma in AP (A-D) and VP (E-H): 70 keV images after enhancement (A, E), Water-based images (B, F), Iodine-based images (C, G) and spectral curves (D, H).
Mingji Yu (2163295)   +7 more
core   +1 more source

Functionalized Au@Cu-Sb-S Nanoparticles for Spectral CT/Photoacoustic Imaging-Guided Synergetic Photo-Radiotherapy in Breast Cancer

open access: yesInternational Journal of Nanomedicine, 2022
Honglei Hu,1,2,* Shuting Zheng,1,2,* Meirong Hou,1,2 Kai Zhu,1,2 Chuyao Chen,1 Zede Wu,1,2 Li Qi,3 Yunyan Ren,1 Bin Wu,4 Yikai Xu,1 Chenggong Yan,1,5 Bingxia Zhao2,6 1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical ...
Hu H   +11 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Spectral CT in patients with acute thoracoabdominal bleeding-a safe technique to improve diagnostic confidence and reduce dose? [PDF]

open access: yes, 2019
Computed tomography (CT) protocols for the detection of bleeding sources often include unenhanced CT series to distinguish contrast agent extravasation from calcification.
Streitparth, Florian   +6 more
core   +1 more source

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