Results 41 to 50 of about 528,301 (219)

A Review of Wine Authentication Using Spectroscopic Approaches in Combination with Chemometrics

open access: yesMolecules, 2021
In a global context where trading of wines involves considerable economic value, the requirement to guarantee wine authenticity can never be underestimated.
Ranaweera K. R. Ranaweera   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Monitoring of Heracleum sosnowskyi Manden Using UAV Multisensors: Case Study in Moscow Region, Russia

open access: yesAgronomy
Detection and mapping of Sosnowsky’s hogweed (HS) using remote sensing data have proven effective, yet challenges remain in identifying, localizing, and eliminating HS in urban districts and regions.
Rashid K. Kurbanov   +7 more
doaj   +1 more source

Heteroarylazo derivatives of cyclohexane-1,3-dione and their metal complexes [PDF]

open access: yesJournal of the Serbian Chemical Society, 2014
The coupling of diazotized 2-aminothiazole and 2-aminobenzo-thiazole with cyclohexane-1,3-dione yielded a new type of tridentate ligand systems (HL). Analytical, IR, 1H NMR, 13C NMR and mass spectral data indicate the existence of the compounds ...
Ummathur Muhammed Basheer   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Urban Green Connectivity Assessment: A Comparative Study of Datasets in European Cities

open access: yesRemote Sensing
Urban biodiversity and ecosystem services depend on the quality, quantity, and connectivity of urban green areas (UGAs), which are crucial for enhancing urban livability and resilience.
Cristiana Aleixo   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Spectrum adapted expectation-maximization algorithm for high-throughput peak shift analysis

open access: yesScience and Technology of Advanced Materials, 2019
We introduce a spectrum-adapted expectation-maximization (EM) algorithm for high-throughput analysis of a large number of spectral datasets by considering the weight of the intensity corresponding to the measurement energy steps.
Tarojiro Matsumura   +4 more
doaj   +1 more source

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