Results 131 to 140 of about 322,666 (307)

Language identification using spectral and prosodic features

, 2015
This book discusses the impact of spectral features extracted from frame level, glottal closure regions, and pitch-synchronous analysis on the performance of language identification systems.
K. Sreenivasa Rao, V. Ramu Reddy, Rao, K Sreenivasa, Reddy, V Ramu, Maity, Sudhamay, Sudhamay Maity   +5 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

PD-Net: Parkinson’s Disease Detection Through Fusion of Two Spectral Features Using Attention-Based Hybrid Deep Neural Network

Information
Parkinson’s disease (PD) is a progressive degenerative brain disease that worsens with age, causing areas of the brain to weaken. Vocal dysfunction often emerges as one of the earliest and most prominent indicators of Parkinson’s disease, with a ...
Munira Islam, Khadija Akter, Md. Azad Hossain, M. Ali Akber Dewan   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Multi-Source Remote Sensing Data-Driven Susceptibility Mapping of Retrogressive Thaw Slumps in the Yangtze River Source Region

Remote Sensing
Despite the ecological sensitivity of the Yangtze River Source Region (YRSR), the current research critically lacks a quantified assessment of the spatial occurrence probability of Retrogressive Thaw Slumps (RTSs) in this specific high-altitude terrain ...
Yun Tian, Taorui Zeng, Qing Lü, Hongwei Jiang, Sihan Yang, Hang Cao, Wenbing Yu   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Modern spectral analysis in HF radar remote sensing. [PDF]

, 1998
High-Frequency (HF) radar systems are currently used to collect wave data. By applying spectral analysis methods, such as the Fast Fourier Transform (FFT) method, to the radar backscatter from the ocean surface, the so-called Doppler spectrum is ...
Vizinho, A., Vizinho, A
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Microscopic Experimental Study on the Crystallization of TBAB-CO2 Hydrate

, 2019
TBAB semi-clathrate hydrate has a huge potential for effective application of carbon dioxide (CO2) capture. Because of the complexity of the crystal structure, the kinetics of TBAB hydrate remains poorly understood.
Zhou Xue-bing, Wu Neng-you, Liang De-qing, Chen Yu-feng   +3 more
core   +1 more source