Results 171 to 180 of about 322,666 (307)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
An Approach to Detect Chronic Obstructive Pulmonary Disease Using UWB Radar-Based Temporal and Spectral Features. [PDF]
Diagnostics (Basel), 2023 Siddiqui HU +8 more
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Insights into Biochemical Sources and Diffuse Reflectance Spectral Features for Colorectal Cancer Detection and Localization. [PDF]
Cancers (Basel), 2022 Saito Nogueira M +7 more
europepmc +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
A new hyperspectral image classification method based on spatial-spectral features. [PDF]
Sci Rep, 2022 Shenming Q, Xiang L, Zhihua G.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Analysis of Spectral Features Based on Water Content of Desert Vegetation
, 2010 By using HR-768 field-portable spectroradiometer made by the Spectra Vista Corporation(SVC) of America, the hyper-spectral data of nine types of desert plants were measured, and the water content of corresponding vegetation was determined by roasting in ...
Zhou Sheng-bin +5 more
core
Investigating the spectral features of the brain meso-scale structure at rest. [PDF]
Hum Brain Mapp, 2021 Iandolo R +5 more
europepmc +1 more source