Results 101 to 110 of about 1,334,336 (314)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Molecules in Cool Stars: The A2Π − X2Σ+ and the B2Σ+ − X2Σ+ Band Systems of CaCl
The Astrophysical JournalCool red giant stars exhibit absorption bands of calcium monochloride (CaCl) in the optical region. In this work, the bands of CaCl corresponding to the A ^2 Π − X ^2 Σ ^+ transition with ${v}^{{\prime} }\leqslant $ 4 and v ″ ≤ 4, and B ^2 Σ ^+ − X ^2 Σ ^
Léo Lavy, Peter F. Bernath
doaj +1 more source
ORFEUS II echelle spectra: On the influence of iron-group line blanketing in the Far-UV spectral range of hot subdwarfs [PDF]
, 2000 J. L. Deetjen
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Spectuner: A Framework for Automated Line Identification of Interstellar Molecules
The Astrophysical Journal Supplement SeriesInterstellar molecules, which play an important role in astrochemistry, are identified using observed spectral lines. Despite the advent of spectral analysis tools in the past decade, the identification of spectral lines remains a tedious task that ...
Yisheng Qiu +6 more
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The A2Π–X2Σ+ Band System of ScO for M-type Star Spectral Analysis
The Astrophysical JournalM-type stars are the most abundant stars in our Galaxy. Their visible spectra are characterized by strong TiO and VO absorption bands with occasional ScO bands near 6000–6100 Å.
Léo Lavy +2 more
doaj +1 more source
Coronal line forest AGN - II. Analysis of the spectral energy distribution
, 2023 Fernando Cerqueira-Campos +5 more
openalex +2 more sources
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Quantum scalar fields in the half-line. A heat kernel/zeta function approach [PDF]
, 2009 In this paper we shall study vacuum fluctuations of a single scalar field with Dirichlet boundary conditions in a finite but very long line. The spectral heat kernel, the heat partition function and the spectral zeta function are calculated in terms of ...
Guilarte, J. Mateos +2 more
core +1 more source