Results 81 to 90 of about 1,340,272 (265)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A new index for detection of submerged aquatic plants under variable quality water: an extension of the soil-line concept

GIScience & Remote Sensing
Submersed aquatic plant (SAP) communities are important determinants of estuarine and lacustrine food web structure, nutrient cycling, and water quality.
Shruti Khanna, Erin L. Hestir, Joaquim Bellvert, Jennifer D. Boyer, Kristen D. Shapiro, Susan L. Ustin   +5 more
doaj   +1 more source

Three-dimensional representation of triple spectral line imaging data as an option for noncontact skin diagnostics. [PDF]

J Biomed Opt, 2022
Ošina I, Spigulis J, Kuzmina I, Dambite L, Berzina A.   +4 more
europepmc   +1 more source

On broad iron K-alpha lines in Seyfert 1 galaxies

, 1995
The X-ray spectrum obtained by Tanaka et al from a long observation of the active galaxy MCG$-6-30-15$ shows a broad iron K$\alpha$ line skewed to low energies.
Brandt, W. N., Fabian, A. C., Inoue, H., Iwasawa, K., Nandra, K., Otani, C., Reynolds, C. S., Tanaka, Y.   +7 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Molecules in Cool Stars: The A2Π − X2Σ+ and the B2Σ+ − X2Σ+ Band Systems of CaCl

The Astrophysical Journal
Cool red giant stars exhibit absorption bands of calcium monochloride (CaCl) in the optical region. In this work, the bands of CaCl corresponding to the A ^2 Π − X ^2 Σ ^+ transition with ${v}^{{\prime} }\leqslant $ 4 and v ″ ≤ 4, and B ^2 Σ ^+ − X ^2 Σ ^
Léo Lavy, Peter F. Bernath
doaj   +1 more source

Skin chromophore mapping by smartphone RGB camera under spectral band and spectral line illumination. [PDF]

J Biomed Opt, 2022
Kuzmina I, Oshina I, Dambite L, Lukinsone V, Maslobojeva A, Berzina A, Spigulis J.   +6 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Spectuner: A Framework for Automated Line Identification of Interstellar Molecules

The Astrophysical Journal Supplement Series
Interstellar molecules, which play an important role in astrochemistry, are identified using observed spectral lines. Despite the advent of spectral analysis tools in the past decade, the identification of spectral lines remains a tedious task that ...
Yisheng Qiu, Tianwei Zhang, Thomas Möller, Xue-Jian Jiang, Zihao Song, Huaxi Chen, Donghui Quan   +6 more
doaj   +1 more source

3D NLTE spectral line formation of lithium in late-type stars. [PDF]

Mon Not R Astron Soc, 2021
Wang EX, Nordlander T, Asplund M, Amarsi AM, Lind K, Zhou Y.   +5 more
europepmc   +1 more source