Results 41 to 50 of about 1,312,433 (296)

Global Collapses and Expansions in Star-Forming Clouds

, 2009
Spectral molecular line profile observations of star-forming molecular clouds sometimes show distinct red asymmetric double-peaked molecular line profiles with weaker blue peaks and stronger red peaks.
Adams, Adelson, Aguti, Arons, Belloche, Bernes, Bian, Carolan, Di Francesco, Evans, Fiege, Fiege, Fuller, Gao, Hammersley, Harvey, Hennebelle, Hogerheijde, Hu, Jørgensen, Kenyon, Keto, Lada, Larson, Lee, Lou, Lou, Lou, Lou, MacLow, Mardones, Matthews, Matzner, Matzner, McKee, Moraghan, Moriarty-Schieven, Myers, Myers, Nakano, Ossenkopf, Ostriker, Park, Park, Park, Rawlings, Redman, Redman, Saito, Schöier, Shang, Shen, Shirley, Shreider, Shu, Shu, Shu, Shu, Su, Tafalla, Tafalla, Tafalla, Thompson, Tsamis, van der Tak, Van Zadelhoff, Velusamy, Wang, Ward-Thompson, Wilner, Wu, Yang Gao, Yu, Yu, Yu-Qing Lou, Zhou, Zhou, Zweibel   +77 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

How to SYN in seven easy steps [PDF]

, 2001
The calculation of expected spectral line strengths and profiles is a powerful tool for the analysis of the solar atmosphere, and other stellar atmospheres.
Anstee, Barklem, Barklem, Holweger, J.E.R. Ross, Kurucz, Mihalas, Nieminen, Nieminen, Peach, Ross, T.A. Nieminen, Thompson   +12 more
core   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Spectral-domain method of moments for the modal analysis of line waveguides [PDF]

, 2023
Giampiero Lovat, Walter Fuscaldo, Massimo Moccia, Giuseppe Castaldi, Vincenzo Galdi, Paolo Burghignoli   +5 more
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

A Spectral Conjugate Gradient Method with Inexact line searches [PDF]

المجلة العراقية للعلوم الاحصائية, 2011
In this paper, a new Spectral Conjugate Gradient (SCG) method for solving unconstrained optimization problems; based on inexact line searches is investigated. The search directions of the new CG method are always sufficient descent.
Abbas Y. Al-Bayati, Basim A. Hassan
doaj   +1 more source

Velocity Modification of Power Spectrum from Absorbing Medium

, 2004
Quantitative description of the statistics of intensity fluctuations within spectral line data cubes introduced in our earlier work is extended to the absorbing media.
A. Lazarian, Cho J., D. Pogosyan, Falgarone E., Goodman J., Green D. A., Kalberla P. M. W., Lazarian A., Lazarian A., Lazarian A., Stenholm L. G., Stutzki J., Velikhov E. P.   +12 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Electronic Spectral Line Shape of a Diatomic Molecule [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1988
The electronic absorption spectral line shape of a diatomic molecule with harmonic potential curves is calculated using the time correlation function formalism.
Reza Islampour, Ali Maghari
doaj