Results 51 to 60 of about 5,257,093 (276)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Spectral Characteristics of Biological Soil Crusts under the Different Types in the Water-Wind Erosion Crisscross Region on the Loess Plateau

, 2018
The study on spectral characteristics of biological soil crust in the water-wind erosion crisscross region in the Loess Plateau has important scientific value for the identification of biological soil crust based on remote sensing technology at regional ...
Sun, WY (reprint author), Northwest A&F Univ, State Key Lab Soil Eros & Dryland Farming Loess P, Yangling 712100, Shaanxi, Peoples R China., Zhang Yue, Mu Xing-min, Tian Yuan-sheng, Sun Wen-yi, Sun, WY (reprint author), Chinese Acad Sci & Minist Water Resources, Inst Soil & Water Conservat, Yangling 712100, Shaanxi, Peoples R China., Zhao Guang-ju, Gao Peng   +7 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Broad line emission from iron K- and L-shell transitions in the active galaxy 1H 0707-495

, 2009
Since the 1995 discovery of the broad iron K-line emission from the Seyfert galaxy MCG-6-30-15 (ref. 1), broad iron K lines have been found in emission from several other Seyfert galaxies, from accreting stellar-mass black holes and even from accreting ...
T. Boller, Reynolds, C., Tanaka, Y, Larsson, J., Reynolds, C.S., Boller, T., Zoghbi, A., Y. Tanaka, G. Miniutti, Brandt, W.N., Zoghbi, A, Blustin, A., Reis, R.C., W. N. Brandt, Ponti, G, Ross, R., Uttley, P., Cadallero-Garcia, M., C. S. Reynolds, Blustin, A. J., Caballero-Garcia, M.D., Young, A.J., P. Uttley, Reynolds, C.S, Miller, J.M., Ross, R.R., A. C. Fabian, Uttley, P, Tanaka, Y., Young, A.J, L. C. Gallo, J. M. Miller, Miniutti, G, Brandt, W. N., G. Ponti, Fabian, A.C., Brandt, W, Blustin, A.J, Reis, R., Reis, R. C., Blustin, A.J., A. J. Blustin, J. Larsson, Ross, R. R., Miller, J.M, A. Zoghbi, R. C. Reis, M. D. Caballero-Garcia, A. J. Young, Ross, R.R, Miller, Jon M., Brandt, W., Gallo, L. C., Fabian, A., Caballero-Garcia, M. D., Ponti, G., Miniutti, G., Larsson, J, R. R. Ross, Gallo, L., Young, A., Fabian, A.C, Fabian, Andy C., Caballero-Garcia, M.D, Boller, T, Reynolds, Christopher S., Miniutti, Giovanni, Gallo, L.C., Miller, J., Reis, R.C, Young, A. J.   +70 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A Spectral Conjugate Gradient Method with Inexact line searches [PDF]

المجلة العراقية للعلوم الاحصائية, 2011
In this paper, a new Spectral Conjugate Gradient (SCG) method for solving unconstrained optimization problems; based on inexact line searches is investigated. The search directions of the new CG method are always sufficient descent.
Abbas Y. Al-Bayati, Basim A. Hassan
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Electronic Spectral Line Shape of a Diatomic Molecule [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1988
The electronic absorption spectral line shape of a diatomic molecule with harmonic potential curves is calculated using the time correlation function formalism.
Reza Islampour, Ali Maghari
doaj