Results 81 to 90 of about 711,060 (330)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Revisiting Near-infrared Features of Kilonovae: The Importance of Gadolinium

The Astrophysical Journal
The observation of the kilonova AT2017gfo and investigations of its light curves and spectra confirmed that neutron star mergers are sites of r -process nucleosynthesis.
Salma Rahmouni, Masaomi Tanaka, Nanae Domoto, Daiji Kato, Kenta Hotokezaka, Wako Aoki, Teruyuki Hirano, Takayuki Kotani, Masayuki Kuzuhara, Motohide Tamura   +9 more
doaj   +1 more source

Optical identification of XMM sources in the CFHTLS

, 2009
We present optical spectroscopic identifications of X-ray sources in ~3 square degrees of the XMM-Large Scale Structure survey (XMM-LSS), also covered by the Canada France Hawaii Telescope Legacy Survey (CFHTLS), obtained with the AAOmega instrument at ...
A. J. Fox, A. Schwope, Alexander, Anderson, Antonucci, Arnouts, Avni, Baldwin, Barger, Bechtold, Bondi, Bondi, Brand, Brandt, Brusa, Brusa, C. S. Stalin, Caccianiga, Caccianiga, Cappelluti, Carrera, Cocchia, Cohen, Comastri, Condon, Croom, Cuillandre, Dye, Elvis, F. Coppolani, Fabbiano, Feruglio, Fiore, Fiore, Fossati, Garcet, Gavignaud, Georgantopoulos, Giacconi, Gibson, Green, Griffiths, Hasinger, Hewett, Hickox, Just, Kauffmann, Kelly, Kewley, Kim, Kim, Krumpe, La Franca, Lawrence, Le Fèvre, Lehmann, Lewis, Lonsdale, Luo, Maccacaro, Miszalski, Oke, Patrick Petitjean, Pickering, Pierre, Pierre, R. Srianand, Reimers, Schiminovich, Schmidt, Schneider, Schultheis, Schwope, Severgnini, Sharp, Shen, Spoon, Steffen, Stern, Stocke, Strateva, Szokoly, Tajer, Tasse, Trump, Ueda, Ueda, Vignali, Wang, Wilkes, Wilkes, Worrall, Worrall, Worsley, Yang, Yuan, Yuan, Zakamska, Zamorani   +98 more
core   +2 more sources

Interpreting the Ionization Sequence in Star-Forming Galaxy Emission-Line Spectra [PDF]

, 2016
High ionization star forming (SF) galaxies are easily identified with strong emission line techniques such as the BPT diagram, and form an obvious ionization sequence on such diagrams.
Allen, James T., Baldwin, Jack A., Crider, Anthony, Ferland, Gary J., Hewett, Paul C., Meskhidze, Helen, Richardson, Chris T.   +6 more
core   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Maser Activity of Organic Molecules toward Sgr B2(N)

The Astrophysical Journal
At centimeter wavelengths, single-dish observations have suggested that the Sagittarius (Sgr) B2 molecular cloud at the Galactic Center hosts weak maser emission from several organic molecules, including CH _2 NH, HNCNH, and HCOOCH _3 . However, the lack
Ci Xue, Anthony Remijan, Alexandre Faure, Emmanuel Momjian, Todd R. Hunter, Ryan A. Loomis, Eric Herbst, Brett McGuire   +7 more
doaj   +1 more source

Defect Detection in Arc-Welding Processes by Means of the Line-to-Continuum Method and Feature Selection

Sensors, 2009
Plasma optical spectroscopy is widely employed in on-line welding diagnostics. The determination of the plasma electron temperature, which is typically selected as the output monitoring parameter, implies the identification of the atomic emission lines ...
Olga M. Conde, Adolfo Cobo, P. Beatriz Garcia-Allende, Jesus Mirapeix, Jose M. Lopez-Higuera   +4 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Identification and Determination of the Bloodstains Dry Time in the Crime Scenes Using Laser-Induced Breakdown Spectroscopy

IEEE Photonics Journal, 2019
The bloodstain is one kind of the most important evidences in crime scenes. Laser-induced breakdown spectroscopy (LIBS) technology was used in this paper to distinguish bloodstains from analogs and determine the time since deposited (TSD) of bloodstains.
Qianqian Wang, Geer Teng, Yu Zhao, Xutai Cui, Kai Wei   +4 more
doaj   +1 more source

Spectroscopic requirements for HALOE: An analysis of the HCl and HF channels [PDF]

Spectral line parameters that have absorption features within the HCl and HF channels of the Halogen Occultation Experiment (HALOE) were evaluated. Line positions and identification of stratospheric and solar absorption features in both channels are ...
Harvey, G. A., Park, J. H., Richardson, D. J., Rinsland, C. P., Russell, J. M., III, Smith, M. A. H.   +5 more
core   +1 more source