Results 91 to 100 of about 5,361,465 (264)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Spectral characterisation of the dicode PPM format [PDF]

, 2005
Dicode pulse position modulation (PPM) is a new modulation format that offers improved sensitivity over digital PPM but at a reduced line-rate. This Letter considers, for the first time, the spectral characterisation of the dicode PPM modulation format ...
Cryan, R.A.
core   +1 more source

Hunting for Sulfur-containing Molecules in Space: A Spectroscopic Characterization of Cyclopropenethione Based on High-level Ab Initio Calculations

The Astrophysical Journal
Cyclopropenethione falls into the class of complex organic molecules but has not yet been observed in the interstellar medium or any circumstellar disks. However, its existence is very likely, and thus this study provides high-level ab initio predictions,
Subhasish Das, Guntram Rauhut
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

The Discovery of 25 μm Interstellar Methanol

The Astrophysical Journal Letters
We present the first astrophysical detection of methanol (CH _3 OH) in the torsional band near 25 μ m. Using high-resolution mid-infrared (MIR) spectroscopy, we identified over 70 gas-phase CH _3 OH absorption lines between 20 and 28 μ m toward the ...
Sarah L. Nickerson, Naseem Rangwala, Keeyoon Sung, Xinchuan Huang, Edward J. Montiel, Curtis DeWitt, Valentin J. M. Le Gouellec, Sean W. J. Colgan, Jason Dittmann, José Pablo Fonfría, Graham M. Harper, Kathleen E. Kraemer, Jialu Li, Conor A. Nixon, Maisie Frances Rashman, Clara Sousa-Silva, Alexander G. G. M. Tielens, William D. Vacca   +17 more
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

High-precision Near-infrared Abundances of Solar Analogs in the YJ Bands

The Astrophysical Journal Supplement Series
We present a near-infrared abundance analysis of 46 solar analogs with known ages, observed with the WINERED WIDE-mode spectrograph at a resolution of λ /Δ λ  = 28,000.
Noriyuki Matsunaga, Takuji Tsujimoto, Daisuke Taniguchi, Hiroaki Sameshima, Shogo Otsubo, Tomomi Takeuchi, Yuki Sarugaku, Ilaria Petralia, Scarlet Elgueta, Matilde Coello-Guzmán, Kei Fukue, Yuji Ikeda, Hideyo Kawakita, Valentina D’Orazi, Giuseppe Bono   +14 more
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Broad line emission from iron K- and L-shell transitions in the active galaxy 1H 0707-495

, 2009
Since the 1995 discovery of the broad iron K-line emission from the Seyfert galaxy MCG-6-30-15 (ref. 1), broad iron K lines have been found in emission from several other Seyfert galaxies, from accreting stellar-mass black holes and even from accreting ...
T. Boller, Reynolds, C., Tanaka, Y, Larsson, J., Reynolds, C.S., Boller, T., Zoghbi, A., Y. Tanaka, G. Miniutti, Brandt, W.N., Zoghbi, A, Blustin, A., Reis, R.C., W. N. Brandt, Ponti, G, Ross, R., Uttley, P., Cadallero-Garcia, M., C. S. Reynolds, Blustin, A. J., Caballero-Garcia, M.D., Young, A.J., P. Uttley, Reynolds, C.S, Miller, J.M., Ross, R.R., A. C. Fabian, Uttley, P, Tanaka, Y., Young, A.J, L. C. Gallo, J. M. Miller, Miniutti, G, Brandt, W. N., G. Ponti, Fabian, A.C., Brandt, W, Blustin, A.J, Reis, R., Reis, R. C., Blustin, A.J., A. J. Blustin, J. Larsson, Ross, R. R., Miller, J.M, A. Zoghbi, R. C. Reis, M. D. Caballero-Garcia, A. J. Young, Ross, R.R, Miller, Jon M., Brandt, W., Gallo, L. C., Fabian, A., Caballero-Garcia, M. D., Ponti, G., Miniutti, G., Larsson, J, R. R. Ross, Gallo, L., Young, A., Fabian, A.C, Fabian, Andy C., Caballero-Garcia, M.D, Boller, T, Reynolds, Christopher S., Miniutti, Giovanni, Gallo, L.C., Miller, J., Reis, R.C, Young, A. J.   +70 more
core   +1 more source

PyEMILI: A New Generation Computer-aided Spectral-line Identifier. II. Emission-line Identification and Plasma Diagnostics of a Sample of Gaseous Nebulae

The Astrophysical Journal Supplement Series
In order to test the robustness and reliability of the new generation spectral-line identifier PyEMILI, as initially introduced in Paper I, in line identification and establish a reference/benchmark dataset for future spectroscopic studies, we run the ...
Zhijun Tu, Xuan Fang, Jorge García-Rojas, Robert Williams, Jifeng Liu   +4 more
doaj   +1 more source