Results 81 to 90 of about 5,361,465 (264)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

iSLAT: the Interactive Spectral-line Analysis Tool for JWST and Beyond

open access: yesThe Astronomical Journal
We present the Interactive Spectral-Line Analysis Tool (iSLAT), a python-based graphical tool that allows users to interactively explore, inspect, and fit line emission observed in molecular spectra. iSLAT adopts a simple slab model in LTE that simulates
Evan G. Jellison   +3 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Hydrogen Atom Collision Processes in Cool Stellar Atmospheres : Effects on Spectral Line Strengths and Measured Chemical Abundances in Old Stars

open access: yes, 2012
The precise measurement of the chemical composition of stars is a fundamental problem relevant to many areas of astrophysics. State-of-the-art approaches attempt to unite accurate descriptions of microphysics, non-local thermodynamic equilibrium (non-LTE)
Barklem, Paul S.,
core   +1 more source

Reading lists - how do you eat yours? [PDF]

open access: yes, 2004
Report of a CELT project on supporting students through innovation and researchStudents at the University of Wolverhampton Business School (UWBS are given reading lists as part of their guides for each module. Learning Centre staff at Compton and Telford
Thompson, Lisa   +2 more
core   +3 more sources

A Self-consistent Treatment of the Line-driving Radiation Force for Active Galactic Nuclei Outflows: New Prescriptions for Simulations

open access: yesThe Astrophysical Journal
Flows driven by photons have been studied for almost a century, and a quantitative description of the radiative forces on atoms and ions is important for understanding a wide variety of systems with outflows and accretion disks, such as active galactic ...
Aylecia S. Lattimer, Steven R. Cranmer
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Improved Hot Line Lists for Minor CN Isotopologues in the X2Σ+, A2Π, and B2Σ+ Systems Using Diagonal Born–Oppenheimer Corrections

open access: yesThe Astrophysical Journal Supplement Series
We present improved hot line lists for optical transitions between the mutually perturbed B ^2 Σ ^+ , A ^2 Π, and X ^2 Σ ^+ states of the minor CN isotopologues ^13 C ^14 N, ^12 C ^15 N, and ^13 C ^15 N.
V. A. Terashkevich   +5 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

ExoMolHR: A Relational Database of Empirical High-resolution Molecular Spectra

open access: yesThe Astrophysical Journal Supplement Series
ExoMolHR is an empirical, high-resolution molecular spectrum calculator for the high-temperature molecular line lists available from the ExoMol molecular database.
Jingxin Zhang   +3 more
doaj   +1 more source

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